A modular hierarchical approach to 3D electron microscopy image segmentation.
A modular hierarchical approach to 3D electron microscopy image segmentation.
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DOI:
10.1016/j.jneumeth.2014.01.022
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发表时间:
2014-04-15
影响因子:
3
通讯作者:
Tasdizen, Tolga
中科院分区:
文献类型:
--
作者:
Liu, Ting;Jones, Cory;Seyedhosseini, Mojtaba;Tasdizen, Tolga
关键词:
The study of neural circuit reconstruction, i.e., connectomics, is a challenging problem in neuroscience. Automated and semi-automated electron microscopy (EM) image analysis can be tremendously helpful for connectomics research. In this paper, we propose a fully automatic approach for intra-section segmentation and inter-section reconstruction of neurons using EM images. A hierarchical merge tree structure is built to represent multiple region hypotheses and supervised classification techniques are used to evaluate their potentials, based on which we resolve the merge tree with consistency constraints to acquire final intra-section segmentation. Then, we use a supervised learning based linking procedure for the inter-section neuron reconstruction. Also, we develop a semi-automatic method that utilizes the intermediate outputs of our automatic algorithm and achieves intra-segmentation with minimal user intervention. The experimental results show that our automatic method can achieve close-to-human intra-segmentation accuracy and state-of-the-art inter-section reconstruction accuracy. We also show that our semi-automatic method can further improve the intra-segmentation accuracy.
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影响因子:
64.8
作者:
Bock, Davi D.;Lee, Wei-Chung Allen;Kerlin, Aaron M.;Andermann, Mark L.;Hood, Greg;Wetzel, Arthur W.;Yurgenson, Sergey;Soucy, Edward R.;Kim, Hyon Suk;Reid, R. Clay
通讯作者:
Reid, R. Clay
DOI:
10.1109/tit.1962.1057692
发表时间:
1962-01-01
期刊:
IRE TRANSACTIONS ON INFORMATION THEORY
影响因子:
--
作者:
HU, M
通讯作者:
HU, M
DOI:
10.1109/tvcg.2009.178
发表时间:
2009-11
影响因子:
5.2
作者:
Jeong WK;Beyer J;Hadwiger M;Vazquez A;Pfister H;Whitaker RT
通讯作者:
Whitaker RT
影响因子:
10.9
作者:
Andres, Bjoern;Koethe, Ullrich;Hamprecht, Fred A.
通讯作者:
Hamprecht, Fred A.
DOI:
10.1023/b:visi.0000022288.19776.77
发表时间:
2004-09-01
影响因子:
19.5
作者:
Felzenszwalb, PF;Huttenlocher, DP
通讯作者:
Huttenlocher, DP