Palladium-Catalyzed Sequential Acylation/Cyanation of Aryl Iodides: A Regiospecific Synthesis of 2-Cyanoaryl Ketones
Palladium-Catalyzed Sequential Acylation/Cyanation of Aryl Iodides: A Regiospecific Synthesis of 2-Cyanoaryl Ketones
复制标题
钯催化芳基碘化物的顺序酰化/氰化：2-氰基芳基酮的区域特异性合成
DOI：
10.1021/acs.joc.5b02710
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发表时间：
2016
影响因子：
3.6
通讯作者：
Chen Wanzhi
中科院分区：
文献类型：
--
作者：
Pan Shanfei;Wu Feifei;Yu Ruicheng;Chen Wanzhi
通过使用酰氯作为酰化试剂和氰化亚铜，开发了钯催化、降冰片烯介导的碘苯酰化/氰化反应。该反应通过使用容易获得的起始原料有效地得到2-氰基芳基酮。
A palladium-catalyzed, norbornene-mediated acylation/cyanation reaction of iodobenzene was developed by the use of acyl chlorides as acylation reagents and cuprous cyanide. The reaction gave the 2-cyanoaryl ketones efficiently by using readily available starting materials.