Deep phenotyping of 34,128 adult patients hospitalised with COVID-19 in an international network study.
Deep phenotyping of 34,128 adult patients hospitalised with COVID-19 in an international network study.
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DOI：
10.1038/s41467-020-18849-z
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发表时间：
2020-10-06
影响因子：
16.6
通讯作者：
Ryan P
中科院分区：
文献类型：
--
作者：
Burn E;You SC;Sena AG;Kostka K;Abedtash H;Abrahão MTF;Alberga A;Alghoul H;Alser O;Alshammari TM;Aragon M;Areia C;Banda JM;Cho J;Culhane AC;Davydov A;DeFalco FJ;Duarte-Salles T;DuVall S;Falconer T;Fernandez-Bertolin S;Gao W;Golozar A;Hardin J;Hripcsak G;Huser V;Jeon H;Jing Y;Jung CY;Kaas-Hansen BS;Kaduk D;Kent S;Kim Y;Kolovos S;Lane JCE;Lee H;Lynch KE;Makadia R;Matheny ME;Mehta PP;Morales DR;Natarajan K;Nyberg F;Ostropolets A;Park RW;Park J;Posada JD;Prats-Uribe A;Rao G;Reich C;Rho Y;Rijnbeek P;Schilling LM;Schuemie M;Shah NH;Shoaibi A;Song S;Spotnitz M;Suchard MA;Swerdel JN;Vizcaya D;Volpe S;Wen H;Williams AE;Yimer BB;Zhang L;Zhuk O;Prieto-Alhambra D;Ryan P
合并症在因2019冠状病毒病（COVID-19）住院的个体中似乎很常见，但对患病率的估计各不相同，对患者既往用药情况知之甚少。在这里，我们描述了因COVID-19住院的成年人的特征，并将其与流感患者进行了比较。我们纳入了34，128名（美国：8362名，韩国：7341名，西班牙：18，425名）COVID-19患者，总结了4811至11，643个独特的聚集特征。COVID-19患者在美国和西班牙以男性为主，但在韩国以女性为主。年龄概况因数据源而异。与2014- 2019年因流感住院的84，585人相比，COVID-19患者通常是男性，更年轻，合并症更少，药物使用更少。虽然保护易受流感影响的群体可能是应对COVID-19的一个有用的起点，但可能需要扩大策略，以反映因COVID-19住院的个人的特殊特征。详细了解COVID-19患者的特征有助于制定公共卫生规划。在这里，作者使用从三个国家的七个数据库中收集的数据来描述超过30，000名因COVID-19入院的患者的特征，并将其与前几年因流感入院的患者进行比较。
Comorbid conditions appear to be common among individuals hospitalised with coronavirus disease 2019 (COVID-19) but estimates of prevalence vary and little is known about the prior medication use of patients. Here, we describe the characteristics of adults hospitalised with COVID-19 and compare them with influenza patients. We include 34,128 (US: 8362, South Korea: 7341, Spain: 18,425) COVID-19 patients, summarising between 4811 and 11,643 unique aggregate characteristics. COVID-19 patients have been majority male in the US and Spain, but predominantly female in South Korea. Age profiles vary across data sources. Compared to 84,585 individuals hospitalised with influenza in 2014-19, COVID-19 patients have more typically been male, younger, and with fewer comorbidities and lower medication use. While protecting groups vulnerable to influenza is likely a useful starting point in the response to COVID-19, strategies will likely need to be broadened to reflect the particular characteristics of individuals being hospitalised with COVID-19. Detailed knowledge of the characteristics of COVID-19 patients helps with public health planning. Here, the authors use routinely-collected data from seven databases in three countries to describe the characteristics of >30,000 patients admitted with COVID-19 and compare them with those admitted for influenza in previous years.
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DOI：
10.15585/mmwr.mm6915e3
发表时间：
2020-04-17
期刊：
MMWR. Morbidity and mortality weekly report
影响因子：
--
作者：
Garg S;Kim L;Whitaker M;O'Halloran A;Cummings C;Holstein R;Prill M;Chai SJ;Kirley PD;Alden NB;Kawasaki B;Yousey-Hindes K;Niccolai L;Anderson EJ;Openo KP;Weigel A;Monroe ML;Ryan P;Henderson J;Kim S;Como-Sabetti K;Lynfield R;Sosin D;Torres S;Muse A;Bennett NM;Billing L;Sutton M;West N;Schaffner W;Talbot HK;Aquino C;George A;Budd A;Brammer L;Langley G;Hall AJ;Fry A
通讯作者：
Fry A
影响因子：
168.9
作者：
Huang, Chaolin;Wang, Yeming;Cao, Bin
通讯作者：
Cao, Bin
影响因子：
15.2
作者：
Brat, Gabriel A.;Weber, Griffin M.;Kohane, Isaac S.
通讯作者：
Kohane, Isaac S.
DOI：
10.1093/jamia/ocaa196
发表时间：
2021-03-01
影响因子：
6.4
作者：
Haendel, Melissa A.;Chute, Christopher G.;Gersing, Ken R.
通讯作者：
Gersing, Ken R.
DOI：
10.1016/s1473-3099(20)30243-7
发表时间：
2020-06-01
期刊：
The Lancet. Infectious diseases
影响因子：
--
作者：
Verity, Robert;Okell, Lucy C;Ferguson, Neil M
通讯作者：
Ferguson, Neil M