Hydrogels from Dextran and Soybean Oil by UV Photo-Polymerization
Hydrogels from Dextran and Soybean Oil by UV Photo-Polymerization
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DOI：
10.1002/app.41446
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发表时间：
2015-02-10
影响因子：
3
通讯作者：
Tai, Hongyun
中科院分区：
文献类型：
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作者：
Omer, Rebaz A.;Hughes, Alan;Tai, Hongyun
以丙烯酸酯基（Dex-A）为官能团的亲水性葡聚糖和疏水性丙烯酸酯环氧大豆油（AESO）为原料，通过紫外光聚合合成了水凝胶。右旋糖酐（M-w 70000 g mol(-1)）与丙烯酰氯和吡啶反应，实现了右旋糖酐的丙烯酰化。采用傅里叶变换红外光谱（FTIR）和核磁共振（NMR）对Dex-A进行了表征。采用Dex-A和AESO的质量比分别为10/90、20/80、30/70、40/60和50/50制备了5种刚性水凝胶。通过红外光谱（FTIR）、热重分析（TGA）和扫描电镜（SEM）对水凝胶进行了表征。实验结果表明，通过改变Dex-A和AESO的比例，可以调整Dex-A/AESO水凝胶的溶胀和释放曲线，从而改变网络结构的亲疏水性和交联密度的平衡。(C) 2014 Wiley期刊公司
In this work, hydrogels were synthesized by UV photo-polymerization of hydrophilic dextran functionalized with acrylate groups (Dex-A) and hydrophobic acrylate epoxidized soybean oil (AESO). The acrylation of dextran was accomplished by reacting dextran (M-w 70,000 g mol(-1)) with acryloyl chloride and pyridine. The Dex-A was characterized by Fourier transform infrared spectroscopy (FTIR) and nuclear magnetic resonance (NMR). Five rigid hydrogels were prepared using the weight ratios of Dex-A and AESO as 10/90, 20/80, 30/70, 40/60, and 50/50. The hydrogels were characterized by FTIR, thermal gravimetric analyses (TGA) and scanning electronic microscopy (SEM). The experimental results demonstrated that the swelling and release profiles of the Dex-A/AESO hydrogels can be tailored by varying the ratio of Dex-A and AESO thus varying the balance of hydrophilicity and hydrophobicity of the network structures and the crosslinking density. (C) 2014 Wiley Periodicals, Inc.