The visual display of regulatory information and networks
The visual display of regulatory information and networks
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DOI：
10.1016/s0962-8924(00)01817-1
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发表时间：
2000-10-01
影响因子：
19
通讯作者：
Maenhaut, C
中科院分区：
文献类型：
--
作者：
Pirson, I;Fortemaison, N;Maenhaut, C
细胞调控和信号转导正变得越来越复杂，有报道称在这些途径的每一步发现了新的交叉信号传导、反馈和前馈调节途径之间以及多种同工酶之间。然而，这一信息需要用数页文字来描述，可以用非常简单的方案来概括，尽管在制定这种方案方面没有达成共识。本文提供了一组简单的规则，允许在易于理解的显示中插入大量信息。
Cell regulation and signal transduction are becoming increasingly complex, with reports of new cross-signalling, feedback, and feedforward regulations between pathways and between the multiple isozymes discovered at each step of these pathways. However, this information, which requires pages of text for its description, can be summarized in very simple schemes, although there is no consensus on the drawing of such schemes. This article presents a simple set of rules that allows a lot of information to be inserted in easily understandable displays.