A prospective study of the use of antibiotics in the Emergency Department of a Chinese University Hospital
A prospective study of the use of antibiotics in the Emergency Department of a Chinese University Hospital
复制标题
中大医院急诊科抗生素使用的前瞻性研究
DOI：
10.1111/ijpp.12335
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发表时间：
2017-02-01
影响因子：
1.8
通讯作者：
Quan, Shuyan
中科院分区：
文献类型：
--
作者：
Zeng, Linan;Hu, Die;Quan, Shuyan
背景抗生素是滥用最广泛的一类药物。本研究的目的是调查抗生素的使用在儿科急诊室在China.MethodsWe进行了前瞻性，横断面研究，在华西第二大学医院儿科急诊室的抗生素使用。从2013年3月25日至4月3日，共纳入500例连续患者。同时收集患者的临床资料，分析抗生素的使用情况。在急诊室最常见的五种疾病是喘息性支气管炎、上呼吸道感染、扁桃体炎、肺炎和腹泻。共有311名儿童（62%）接受了抗生素治疗。处方抗生素主要为头孢菌素类和青霉素类。51例患者使用了一种以上的抗生素。总的来说，75%的抗生素处方是头孢菌素类。超过四分之三患有喘息性支气管炎的幼儿接受了抗生素治疗。抗生素的使用与上呼吸道感染或扁桃体炎的儿童大于20%的最大推荐的欧洲监测抗菌药物Consumption.ConclusionsThe大多数儿童参加急诊科接受抗生素。对于许多情况，抗生素的使用是不合适的。
BackgroundAntibiotics are one of the most widely misused group of medicines. The aim of this study was to investigate the use of antibiotics in one of the paediatric emergency departments in China.MethodsWe performed a prospective, cross-sectional study of antibiotic use in the paediatric emergency room of West China Second University Hospital. A total of 500 consecutive patients from March 25 to April 3 2013 were included. Clinical details of the patients were also collected in order to analyse antibiotic use.Key findingsThe median age of patients was 2years 2months. The five most common conditions seen in the emergency department were wheezy bronchitis, upper respiratory tract infections, tonsillitis, pneumonia and diarrhoea. A total of 311 children (62%) received antibiotics. The antibiotics prescribed were predominantly cephalosporins and penicillins. More than one antibiotic was used in 51 patients. In total, 75% of the antibiotics prescribed were cephalosporins. More than three-quarters of the young children with wheezy bronchitis received antibiotics. Antibiotic use for children with an upper respiratory tract infections or tonsillitis was greater than the 20% maximum recommended by the European Surveillance of Antimicrobial Consumption.ConclusionsThe majority of children attending the emergency department received antibiotics. For many of the conditions, the use of antibiotics was inappropriate.