Sleep patterns in children with autistic spectrum disorders: a prospective cohort study.
Sleep patterns in children with autistic spectrum disorders: a prospective cohort study.
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DOI：
10.1136/archdischild-2013-304083
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发表时间：
2014-02
影响因子：
5.2
通讯作者：
Emond AM
中科院分区：
文献类型：
--
作者：
Humphreys JS;Gringras P;Blair PS;Scott N;Henderson J;Fleming PJ;Emond AM
目的探讨自闭症谱系障碍(ASDS)儿童的纵向睡眠模式。前瞻性纵向研究使用雅芳父母和孩子的纵向研究，出生于1991-1992年的英国队列。在6个 月至11 年的8个时间点，通过问卷调查的方式收集父母的睡眠时间报告。从健康和教育记录中确定了在11岁时被诊断为ASD的儿童(n=73)。从30 月到11 岁，自闭症儿童每天的睡眠时间比同时代的对照组少17-43 分钟。婴儿时期的总睡眠时间没有显著差异，但从30 个月开始，患有自闭症的儿童睡眠时间比同龄人少，在调整了性别、种族、高胎次和癫痫后，这种差异仍然显著。总睡眠时间的减少完全是由于夜间睡眠时间的变化，而不是白天的睡眠时间。晚睡时间和早醒时间缩短了夜间睡眠时间。患有自闭症的儿童从30个 月开始，也明显地经常醒来(每晚3次或更多)。在18个月到30个 月之间(p=0.04)和在30个月到42个 月之间(p=0.02)，个体内睡眠时间在相邻时间点上的>；1SD的特定年龄减少是自闭症的预测因素。自闭症儿童的睡眠时间从30 月开始减少，并持续到青春期。
To investigate longitudinal sleep patterns in children with autistic spectrum disorders (ASDs). Prospective longitudinal study using Avon Longitudinal Study of Parents and Children, an English cohort born in 1991–1992. Parental reports of sleep duration were collected by questionnaires at 8 time points from 6 months to 11 years. Children with an ASD diagnosis at age 11 years (n=73) were identified from health and education records. From aged 30 months to 11 years old, children with ASD slept for 17–43 min less each day than contemporary controls. No significant difference in total sleep duration was found in infancy, but from 30 months of age children with ASD slept less than their peers, a difference that remained significant after adjusting for sex, ethnicity, high parity and epilepsy. The reduction in total sleep was wholly due to changes in night rather than daytime sleep duration. Night-time sleep duration was shortened by later bedtimes and earlier waking times. Frequent waking (3 or more times a night) was also evident among the children with ASD from 30 months of age. Age-specific decreases of >1SD within individuals in sleep duration across adjacent time points was a predictor of ASD between 18 months and 30 months of age (p=0.04) and from 30 months to 42 months (p=0.02). Sleep duration in children with ASD is reduced from 30 months of age and persists until adolescence.
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影响因子：
4.4
作者：
Cortesi, Flavia;Giannotti, Flavia;Valente, Donatella
通讯作者：
Valente, Donatella
影响因子：
4.4
作者：
Giannotti, Flavia;Cortesi, Flavia;Valente, Donatella
通讯作者：
Valente, Donatella
影响因子：
4.4
作者：
Scott, Nicola;Blair, Peter S.;Gringras, Paul
通讯作者：
Gringras, Paul
影响因子：
3.1
作者：
Schreck, KA;Mulick, JA;Smith, AF
通讯作者：
Smith, AF
影响因子：
--
作者：
Gringras, P.;Gamble, C.;Appleton, R.
通讯作者：
Appleton, R.