A Suggested Pioneer Organism for the Wächtershäuser Origin of Life Hypothesis
A Suggested Pioneer Organism for the Wächtershäuser Origin of Life Hypothesis
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Wächtershäuser 生命起源假说的先锋生物
DOI：
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发表时间：
2011
影响因子：
2
通讯作者：
F. A. Kundell
中科院分区：
文献类型：
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作者：
F. A. Kundell
提出了Wächtershäuser生命起源假说的一种建议的先锋生物。在这种情况下，一个立方的黄铁矿晶体边缘作为催化表面的生产的原核酸。计算分析表明，空的立方硫铁矿边缘可以由铁（II）和磷酸氢填充，并以扭曲的五羰基铁覆盖。然后形成一种桥接的硫化铁，堵塞了边缘的一侧。然后，边缘另一侧的羰基可以与现有的尿嘧啶或胞嘧啶反应，生成氮铁羰基中间体。这种中间体充当一氧化碳和氢分子聚合的自由基引发剂。在第四个碳加入到链上后，聚合通过生成浓缩核糖的环而终止。最终产物是一种原核酸，一种先锋生物。
A suggested pioneer organism for the Wächtershäuser origin of life hypothesis is presented. In this scenario, a cubic pyrite crystal edge serves as a catalytic surface for the production of a proto-nucleic acid. Computational analysis demonstrates how the vacant cubic pyrite edge could be populated by iron(II) and hydrogen phosphate, capped with a distorted iron pentacarbonyl. A bridging iron sulfide then forms blocking one side of the edge. The carbonyl on the other side of the edge can then react with either existing uracil or cytosine, to produce a nitrogen-iron carbonyl intermediate. This intermediate serves as a free radical initiator for a polymerization of carbon monoxide and molecular hydrogen. After the fourth carbon is added to the chain, the polymerization is terminated by ring formation yielding a condensed ribose. The resultant product is a proto-nucleic acid, a pioneer organism.