Recruitment methods employed in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial.
Recruitment methods employed in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial.
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DOI：
10.1177/1740774508100974
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发表时间：
2009-02
期刊：
影响因子：
--
通讯作者：
Marcus P
中科院分区：
文献类型：
--
作者：
Gren L;Broski K;Childs J;Cordes J;Engelhard D;Gahagan B;Gamito E;Gardner V;Geisser M;Higgins D;Jenkins V;Lamerato L;Lappe K;Lowery H;McGuire C;Miedzinski M;Ogden S;Tenorio S;Watt G;Wohlers B;Marcus P
前列腺癌、肺癌、结直肠癌和卵巢癌筛查试验(PLCO)是一项由美国国家癌症研究所(NCI)资助的随机对照试验，旨在评估某些筛查测试是否可以降低前列腺癌、肺癌、结直肠癌和卵巢癌的死亡率。为了获得足够的统计能力，有必要招募超过15万名健康志愿者。招募工作从1993年开始，2001年结束。我们的目标是评估10个PLCO筛查中心采用的招聘方法的成功程度。我们还为我们最成功的战略--直接邮寄--提供了招聘收益和成本的估计。每个筛选中心都选择了自己的招募方法。在整个招聘期内，根据需要改变方法。对于这份手稿，每个筛选中心的代表都提供了所使用的方法及其成功的信息。在美国，1993至2001年间，10个筛查中心招募了154,934名研究参与者。根据参与者的自我报告，估计95%的人是通过直接邮件招募的。总体而言，直接邮寄的注册收益率为1.0%。个人中心招生收益率从0.7%到3.8%不等。每个注册参与者的直接邮寄成本为9.64-35.38美元，不包括人员成本。在各个筛查中心，关于招聘过程的数字数据并不一致。这份手稿中的数字数据是基于10个中心中的5个的经验。直接邮寄，使用营利性和非营利性(包括政府)组织的姓名和地址名册，是最成功和最常用的招聘方法。其他招聘战略，如社区外联和使用大众媒体，可以成为直接邮寄招聘少数族裔人口的重要辅助手段。
The Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial (PLCO) is a US National Cancer Institute (NCI)-funded randomized controlled trial designed to evaluate whether certain screening tests reduce mortality from prostate, lung, colorectal, and ovarian cancer. To obtain adequate statistical power, it was necessary to enroll over 150,000 healthy volunteers. Recruitment began in 1993 and ended in 2001. Our goal is to evaluate the success of recruitment methods employed by the 10 PLCO screening centers. We also provide estimates of recruitment yield and cost for our most successful strategy, direct mail. Each screening center selected its own methods of recruitment. Methods changed throughout the recruitment period as needed. For this manuscript, representatives from each screening center provided information on methods utilized and their success. In the United States between 1993 and 2001, ten screening centers enrolled 154,934 study participants. Based on participant self-report, an estimated 95% of individuals were recruited by direct mail. Overall, enrollment yield for direct mail was 1.0%. Individual center enrollment yield ranged from 0.7% to 3.8%. Cost per enrolled participant was $9.64–35.38 for direct mail, excluding personnel costs. Numeric data on recruitment processes were not kept consistently at individual screening centers. Numeric data in this manuscript are based on the experiences of 5 of the 10 centers. Direct mail, using rosters of names and addresses from profit and not-for-profit (including government) organizations, was the most successful and most often used recruitment method. Other recruitment strategies, such as community outreach and use of mass media, can be an important adjunct to direct mail in recruiting minority populations.