EFFECTS OF EXERCISE TRAINING MODALITY ON GLUCOSE-TOLERANCE IN MEN WITH ABNORMAL GLUCOSE REGULATION
EFFECTS OF EXERCISE TRAINING MODALITY ON GLUCOSE-TOLERANCE IN MEN WITH ABNORMAL GLUCOSE REGULATION
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DOI：
10.1055/s-2007-1021061
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发表时间：
1994-08-01
影响因子：
2.5
通讯作者：
HURLEY, BF
中科院分区：
文献类型：
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作者：
SMUTOK, MA;REECE, C;HURLEY, BF
为了确定运动训练方式对糖耐量异常男性的影响，对26名未经训练的男性(年龄54+/-9岁；均值+/-SD)进行了研究，其中非胰岛素依赖型糖尿病(N=8)、糖耐量受损(IGT)(N=12)或高胰岛素血症伴正常糖耐量(N=6)的男性分别在20wk的力量训练(ST)(N=8)、有氧(跑步机/慢跑)训练(AT)(N=8)和不运动(对照组；N=10)前后进行了研究。在禁食12-14小时后，在训练前后进行标准口服葡萄糖耐量试验(OGTT)，测定血糖和胰岛素浓度。ST程序显著降低了OGTT曲线下的总血糖面积(mmol.l(-1).120min(-1))(1348+/-251vs1190+/-329，p<；0.05)，以及摄入葡萄糖后60min(p<；0.05)、90min(p<；0.05)和120min(p<；0.05)的血糖水平(mmol.l(-1))。力量训练还降低了OGTT曲线下的血浆总胰岛素面积pmol.l(-1).120min(-1)(60082+/-25467 vs 46727+/-11273，p<；0.05)以及空腹(p<；0.05)、摄入葡萄糖后90分钟(p<；0.01)和120min(p<；0.05)的血浆胰岛素水平(pmol.l(-1))。所有患有IGT的男性(每训练组4人)在训练后糖耐量正常化。ST组和AT组的OGTT结果无显著差异，对照组也未见明显变化。因此，在糖调节异常的男性中，力量训练可以改善葡萄糖耐量，降低对葡萄糖摄入的胰岛素反应，其程度与有氧训练相同。
To determine the effects of exercise training modality on glucose tolerance in men with untreated abnormal glucose regulation, 26 untrained men (age 54 +/- 9 years; mean +/- SD) with either non-insulin-dependent diabetes mellitus (N = 8), impaired glucose tolerance (IGT) (N = 12) or hyperinsulinemia with normal glucose tolerance (N = 6) were studied before and after 20 wk of either strength training (ST) (N = 8), aerobic (treadmill walk/jog) training (AT) (N = 8), or no exercise (control group; N = 10). Plasma concentrations of glucose and insulin were measured after a 12-14 hr fast and during a standard oral glucose tolerance test (OGTT) before and after training. The ST program significantly reduced total plasma glucose area (mmol.l(-1).120 min(-1)) under the OGTT curve (1348 +/- 251 vs 1190 +/- 329, p < 0.05), and plasma glucose levels (mmol.l(-1)) at 60 min (p < 0.05), 90 min (P < 0.05), and 120 min (p < 0.05) after glucose ingestion. Strength training also lowered the total plasma insulin area pmol.l(-1).120 min(-1)) under the OGTT curve (60082 +/- 25467 vs 46727 +/- 11273, p < 0.05) as well as plasma insulin levels (pmol.l(-1)) at fasting (p < 0.05) and at 90 min (p < 0.01) and 120 min (p < 0.05) after glucose ingestion. All men with IGT (four in each training group) normalized their glucose tolerance following the training. There were no significant differences in OGTT results between ST and AT and no changes were observed in the control group. Thus, strength training improves glucose tolerance and reduces insulin response to glucose ingestion to the same extent as aerobic training in men with abnormalities in glucose regulation.