Prevalence of chronic kidney disease in an urban Mexican population
Prevalence of chronic kidney disease in an urban Mexican population
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DOI：
10.1111/j.1523-1755.2005.09702.x
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发表时间：
2005-08-01
影响因子：
19.6
通讯作者：
Paniagua, R
中科院分区：
文献类型：
--
作者：
Amato, DK;Alvarez-Aguilar, C;Paniagua, R
背景资料。本研究的主要目的是评估居住在墨西哥的墨西哥城市人口中慢性肾脏疾病的患病率，并评估某些生物和社会经济条件作为肾脏疾病发展的危险因素。一项以人群为基础的横断面调查，包括3564名年龄18岁的男女患者，他们是从莫雷利亚市初级保健机构分配的患者名单中随机挑选出来的。每个患者都获得了关于个人目前健康状况、肾脏疾病、糖尿病、高血压或近亲心脏病的调查问卷，人体测量和血压测量，以及用于测量血糖、血尿素氮和肌酐的血和尿样。肌酐清除率(Ccr)按Cockcroft-Gault公式计算。患者被归入肾脏疾病预后质量倡议指南建立的5个CCR类别中的1个。15毫升/分的患病率为1142/百万，60毫升/分的患病率为80,788/百万。饮酒和吸烟、女性、年龄和65岁、小学文化程度和每天收入4.00美元与Ccr下降显著相关。这一人群中慢性肾脏疾病的患病率与工业化国家相似。如果这些数字与整个墨西哥人口的数字相似，那么目前该国每4名需要肾脏替代疗法的患者中只有1人能够获得这种疗法。
Background. The present study was primarily designed to assess the prevalence of chronic kidney disease in a Mexican urban population residing in Mexico and to evaluate certain biologic and socioeconomic conditions as risk factors for the development of renal disease.Methods. A population-based cross-sectional survey was conducted, which included 3564 patients of either gender aged > 18 years, who were randomly selected from lists of patients assigned to primary care facilities in the city of Morelia. A questionnaire about personal current health status, kidney disease, diabetes, hypertension, or heart disease in close relatives, anthropometric and blood pressure measurements, and blood and urine samples to measure glucose, blood urea nitrogen, and creatinine was obtained for each patient. Creatinine clearance (Ccr) was calculated by the Cockcroft-Gault formula. Patients were classified in 1 of the 5 Ccr categories established by the Kidney Disease Outcomes Quality Initiative guidelines.Results. The prevalence rate of Ccr < 15 mL/min was 1142 per million population, and that of Ccr < 60mL/min 80,788 per million population. Alcohol and tobacco consumption, female gender, age > 65 years, educational level < primary school, and income < US $4.00/day were significantly associated with reduced Ccr.Conclusion. Chronic kidney disease prevalence in this population is similar to that seen in industrialized countries. If these figures are similar to those of the entire Mexican population, only 1 out of 4 patients requiring renal replacement therapy in the country currently has access to it.