Validation of diffusion tensor MRI-based muscle fiber tracking
Validation of diffusion tensor MRI-based muscle fiber tracking
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DOI：
10.1002/mrm.10198
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发表时间：
2002-07-01
影响因子：
3.3
通讯作者：
Gore, JC
中科院分区：
文献类型：
--
作者：
Damon, BM;Ding, ZH;Gore, JC
弥散张量（DT） MRI纤维跟踪可能用于体内结构分析。本研究的目的是定量评估DT-MRI纤维跟踪算法在体内测量骨骼肌纤维取向（笔划）的能力。用DT-MRI （θ (DT-MRI)）和直接解剖检查（DAI） （θ (DAI)）测量5只成年Sprague-Dawley大鼠腓骨外侧肌的穿刺角（θ）。平均θ (DT-MRI)与平均θ (DAI)无显著差异。此外，两种方法高度相关（r = 0.89）， theta（DT-MRI）对theta（DAI）的回归导致斜率与1无显著差异，截距与零无显著差异。这些数据表明，本文所实施的基于dt - mri的纤维跟踪是小型动物骨骼肌体内结构分析的有效工具，(C) 2002 Wiley-Liss, Inc。
Diffusion-tensor (DT) MRI fiber tracking may potentially be used for in vivo structural analysis. The purpose of this study was to assess quantitatively the ability of a DT-MRI fiber-tracking algorithm to measure the fiber orientation (pennation) in skeletal muscle in vivo. In five adult Sprague-Dawley rats, the pennation angle (theta) was measured in the rat lateral gastrocnemius with DT-MRI (theta(DT-mRI)) and by direct anatomical inspection (DAI) (theta(DAI)). The mean theta(DT-MRI) was not significantly different from the mean theta(DAI). In addition, the two methods were highly correlated (r = 0.89) and the regression of theta(DT-MRI) on theta(DAI) resulted in a slope not significantly different from 1 and an intercept not significantly different from zero. These data indicate that DT-MRI-based fiber tracking as implemented here is a valid tool for in vivo structural analysis of small-animal skeletal muscle, (C) 2002 Wiley-Liss, Inc.