Epidemiologic survey of dementia in a community-dwelling Brazilian population
Epidemiologic survey of dementia in a community-dwelling Brazilian population
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DOI：
10.1097/00002093-200204000-00007
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发表时间：
2002-04-01
影响因子：
2.1
通讯作者：
Nitrini, R
中科院分区：
文献类型：
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作者：
Herrera, E;Caramelli, P;Nitrini, R
作者报告了社区居住的巴西老年人口中痴呆症的患病率，并将患病率数据与教育和社会经济水平相关联。该研究在巴西的Catanduva进行。共有1，656名年龄在65岁或以上的随机选择的受试者提交了健康问卷，简易精神状态检查（MMSE）和Pfeffer功能活动问卷（PFAQ）。根据PFAQ和MMSE评分，选择受试者进行临床、神经学和认知评估。被诊断为痴呆的受试者接受实验室检查和脑计算机断层扫描（CT）。118名受试者被诊断为痴呆，患病率为7.1%。主要临床诊断为阿尔茨海默病（AD; 55.1%）、血管性痴呆（9.3%）和AD合并脑血管病（14.4%）。患病率随着年龄的增长而增加，女性患病率更高。与教育程度呈负相关（在受过8年或8年以上教育的人中为3.5%，在文盲中为12.2%）。多因素分析显示，这三个变量与痴呆症之间存在显着关联。巴西人群中痴呆的患病率为7.1%，AD是最常见的诊断。年龄、女性和低教育水平与痴呆症的高患病率显著相关。
The authors report the prevalence of dementia in a community-dwelling Brazilian elderly population and correlate prevalence data with educational and socioeconomic levels. The study was conducted in Catanduva, Brazil. A total of 1,656 randomly selected subjects aged 65 years or more were submitted to a health questionnaire, the Mini-Mental State Examination (MMSE), and the Pfeffer Functional Activities Questionnaire (PFAQ). According to the PFAQ and MMSE scores, selected subjects were submitted to clinical, neurologic, and cognitive evaluations. The subjects diagnosed with dementia underwent laboratory tests and brain computed tomography (CT). Dementia was diagnosed in 118 subjects, corresponding to a prevalence of 7.1%. The main clinical diagnoses were Alzheimer disease (AD; 55.1%), vascular dementia (9.3%), and AD with cerebrovascular disease (14.4%). The prevalence increased with age and was higher in women. There was an inverse association with education (3.5% among persons with 8 or more years of schooling to 12.2% among those who were illiterate). Multivariate analysis disclosed significant association between these three variables and dementia. The prevalence of dementia in this Brazilian population was 7.1%, and AD was the most frequent diagnosis. Age, female gender, and low educational level were significantly associated with a higher prevalence of dementia.