Interictal electromagnetic source imaging in focal epilepsy: practices, results and recommendations
Interictal electromagnetic source imaging in focal epilepsy: practices, results and recommendations
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DOI：
10.1097/wco.0b013e3283081e23
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发表时间：
2008-08-01
影响因子：
4.8
通讯作者：
Huiskamp, Geertjan
中科院分区：
文献类型：
--
作者：
Leijten, Frans S. S.;Huiskamp, Geertjan
综述的目的发作间期癫痫样活动的电磁源成像与脑电图或脑磁图似乎是合理的第一步，在定位致痫灶的部分癫痫。然而，缺乏标准化有助于一个不值得低调的“图像”的电磁源成像。经过临床和技术回顾，我们提出了一个实用的指南如何应用电磁源imaging.Recent findingsWe发现25个临床研究电磁源成像在靶向癫痫手术在最近的文献中，大多数使用脑磁图。电磁源成像的可行性在75%左右。由于缺乏公平的比较，脑磁图是否上级脑电图仍然没有得到解决。临床研究尚未采用所有技术可能性。定位精度似乎很高，但研究缺乏统一的方法，目标和结果参数。因此，电磁源成像在术前检查中的最终位置仍有待确定。诊断潜力可能是最高的颞外癫痫，最低的内侧颞叶epilepsy.SummaryElectromagnetic source imaging技术已经发展，可以提供有价值的定位信息，在术前评估癫痫患者。在进一步的临床研究能够更好地确定其在局灶性癫痫术前评估中的作用之前，需要对该技术进行标准化。一个相对容易的，逐步的数据采集和分析协议。
Purpose of reviewElectromagnetic source imaging of interictal epileptiform activity with electroencephalography or magnetoencephalography seems a logical first step in locating the epileptogenic zone in partial epilepsy. However, a lack of standardization contributes to an undeserved low-key 'image' of electromagnetic source imaging. After a clinical and technical review, we propose a practical guide how to apply electromagnetic source imaging.Recent findingsWe found 25 clinical studies of electromagnetic source imaging in targeting epilepsy surgery in the recent literature, mostly using magnetoencephalography. Feasibility of electromagnetic source imaging is around 75%. Whether magnetoencephalography is superior to electroencephalography is still unresolved, because fair comparisons are lacking. Clinical studies have not yet adopted all technical possibilities. Localization accuracy seems high, but studies lack uniformity regarding methods, goals and outcome parameters. Therefore, the final place of electromagnetic source imaging in the presurgical work-up is still to be determined. The diagnostic potential is probably highest in extratemporal epilepsies, and lowest in mesial temporal lobe epilepsy.SummaryElectromagnetic source imaging has evolved technically and can provide valuable localization information in the presurgical evaluation of patients with epilepsy. Standardization of the technique is required, before further clinical studies can better establish its role in presurgical evaluation of focal epilepsy. A relatively easy, stepwise data acquisition and analysis protocol are proposed.