Development of Tube Radial Distribution Chromatography Based on Phase-Separation Multiphase Flow Created via Pressure Loss
Development of Tube Radial Distribution Chromatography Based on Phase-Separation Multiphase Flow Created via Pressure Loss
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DOI：
10.2116/analsci.19n007
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发表时间：
2019-03
影响因子：
1.6
通讯作者：
Susumu Wada;K. Tsukagoshi;K. Tsuchiya;K. Hirota;K. Yamashita;M. Murata
中科院分区：
文献类型：
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作者：
Susumu Wada;K. Tsukagoshi;K. Tsuchiya;K. Hirota;K. Yamashita;M. Murata
提出了一种基于温度变化相变产生相分离多相流的管径向分布色谱分析方法。这些系统通常需要一个包含水浴和搅拌器的温度控制装置。在这里，我们提出了一种新型的无冷却装置的超临界流体控制系统，该系统通过内径50μm、长550 cm的毛细管内的压力损失来实现相变。用开发的TRDC系统成功地分离了模型分析物，提供了一个简化的平台，有助于阐明基于毛细管内相变的TRDC的工作原理。
A tube radial distribution chromatography (TRDC) method based on phase-separated multiphase flow created through phase transformation via temperature change has been developed. These systems typically required a temperaturecontrolling device containing a water bath and a stirrer. Herein, we proposed a novel TRDC system without a cooling device, where the phase transformation was achieved via pressure loss in a capillary tube of 50 μm inner diameter and 550 cm length. Model analytes were successfully separated with the developed TRDC system, which provided a simplified platform and helped to clarify the operating principle of TRDC based on phase transformation in a capillary tube.