Pulmonary blood flow and tissue volume: model analysis of rebreathing estimation methods.
Pulmonary blood flow and tissue volume: model analysis of rebreathing estimation methods.
复制标题
肺血流量和组织体积:再呼吸估计方法的模型分析。
DOI:
10.1152/jappl.1983.55.1.205
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发表时间:
1983
期刊:
影响因子:
--
通讯作者:
Saidel,GM
中科院分区:
文献类型:
--
作者:
Burma,GM;Saidel,GM
As the basis for comparing rebreathing methods of estimating pulmonary blood flow (Q) and tissue-capillary volume (Vtc), we use a dynamic mass-balance model for gas species having different physicochemical properties (e.g., He, CO, C2H2). The model accounts for the effects of ventilation and perfusion inhomogeneities, breathing pattern variation, lung and rebreathing-bag volumes, and recirculation. Also, we examine the variability of the estimates caused by random error. In addition to analyzing two well-known methods, we show how an appropriate synthesis of these methods can lead to improved estimates.