Pulmonary blood flow and tissue volume: model analysis of rebreathing estimation methods.

Pulmonary blood flow and tissue volume: model analysis of rebreathing estimation methods.
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肺血流量和组织体积:再呼吸估计方法的模型分析。

DOI:
10.1152/jappl.1983.55.1.205
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发表时间:
1983
期刊:
Journal of applied physiology: respiratory, environmental and exercise physiology
影响因子:
--
通讯作者:
Saidel,GM
Saidel,GM
中科院分区:
--
文献类型:
--
作者:
Burma,GM;Saidel,GM

文献摘要

被引文献

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作为比较估计肺血流量(Q)和组织毛细血管容积(Vtc)的再呼吸方法的基础,我们使用具有不同物理化学性质的气体种类的动态质量平衡模型(例如,He、CO、C2H2)。该模型考虑了通气和灌注不均匀性、呼吸模式变化、肺和再呼吸袋容积以及再循环的影响。此外,我们还研究了由随机误差引起的估计值的变异性。除了分析两个众所周知的方法,我们展示了如何适当的合成这些方法可以导致改进的估计。
As the basis for comparing rebreathing methods of estimating pulmonary blood flow (Q) and tissue-capillary volume (Vtc), we use a dynamic mass-balance model for gas species having different physicochemical properties (e.g., He, CO, C2H2). The model accounts for the effects of ventilation and perfusion inhomogeneities, breathing pattern variation, lung and rebreathing-bag volumes, and recirculation. Also, we examine the variability of the estimates caused by random error. In addition to analyzing two well-known methods, we show how an appropriate synthesis of these methods can lead to improved estimates.