Outcome of Living-Donor Liver Transplantation Using Grafts from Donors Treated for Fatty Liver
Outcome of Living-Donor Liver Transplantation Using Grafts from Donors Treated for Fatty Liver
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DOI:
10.12659/aot.920677
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发表时间:
2020-01-10
影响因子:
1.1
通讯作者:
Shimamura, Tsuyoshi
中科院分区:
文献类型:
--
作者:
Fujii, Yuki;Kawamura, Norio;Shimamura, Tsuyoshi
Background: The aim of this study was to determine the efficacy of treating donors' fatty liver (FL) and to assess early graft function in recipients who received treated FL grafts in living-donor liver transplantation (LDLT).Material/Methods: Data were collected for adult-to-adult LDLTs. Donors diagnosed with FL (FL group) received diet-exercise and pharmacological treatment. The perioperative findings and early transplanted graft function were compared with those of donors without FL (non-FL group) during the same period.Results: Of 30 donors, 8 were determined to have FL The median duration of treatment for FL was 58 days. The liver-to- spleen attenuation ratios on CT scan in the FL group were significantly improved after treatment: 0.95 (0.62-1.06) to 1.2 (1.12-1.46) (P=0.003). Liver biopsy prior to donor surgery showed