PLASMA GROWTH HORMONE AFTER ARGININE INFUSION - CLINICAL EXPERIENCES
PLASMA GROWTH HORMONE AFTER ARGININE INFUSION - CLINICAL EXPERIENCES
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DOI：
10.1056/nejm196702232760803
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发表时间：
1967-01-01
影响因子：
158.5
通讯作者：
MCKUSICK, VA
中科院分区：
文献类型：
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作者：
MERIMEE, TJ;RABINOWITZ, D;MCKUSICK, VA
在正常的女性和在已烯雌酚预处理的男性输注精氨酸一氯化物，其次是一致的血浆人生长激素的显着上升。达到的血浆水平与胰岛素诱导的低血糖后达到的水平相当。在大量的个人经验中，输注完全没有副作用，并证明是调查疑似下丘脑功能障碍的有用工具。对阴性反应的解释（如未能观察到血浆生长激素的增加）表示了某些保留意见。
In normal females and in stilbestrol-pretreated males infusion of arginine monochloride was followed consistently by a significant rise in plasma human growth hormone. The plasma levels attained were comparable to those achieved after insulin-induced hypoglycemia. The infusion was entirely without side effects in a large personal experience, and proved a useful tool in the investigation of suspected hypothalamicopituitary disorders. Certain reservations concerning interpretation of a negative response (such as failure to observe an increment in plasma growth hormone) are expressed.