Long-term storage of gametes and gonadal tissues at room temperatures: the end of the ice age?
Long-term storage of gametes and gonadal tissues at room temperatures: the end of the ice age?
复制标题
在室温下长期储存配子和性腺组织：冰河时代的结束？
DOI：
10.1007/s10815-021-02392-x
复制
发表时间：
2022
影响因子：
3.1
通讯作者：
Hubel,Allison
中科院分区：
文献类型：
--
作者：
Comizzoli,Pierre;Loi,Pasqualino;Patrizio,Pasquale;Hubel,Allison
长期保存高质量的活精子、卵子、胚胎和性腺组织对人类生殖医学以及牲畜、实验室和野生物种的种群管理至关重要。令人鼓舞的发现表明，配子或性腺组织的结构和功能可以在脱水后悬浮在海藻糖玻璃中，然后在超零温度下保存，而不是使用冷冻温度。随着生育保存和生物银行的新时代即将开始，必须仔细研究常温种质保存的优势、需求和意义。虽然很有希望，但替代生物银行策略的发展并不一定意味着“冰河时代”（冷冻保存）的结束。
Long-term preservation of viable spermatozoa, eggs, embryos, and gonadal tissues of good quality is essential in human reproductive medicine and for the population management of livestock, laboratory, and wild species. Instead of using freezing temperatures, encouraging findings indicate that structures and functions of gametes or gonadal tissues can be suspended in trehalose glass after dehydration and then preserved at supra-zero temperatures. As a new era in fertility preservation and biobanking is about to start, the advantages, needs, and implications of germplasm storage at room temperatures must be carefully examined. Although very promising, the development of alternate biobanking strategies does not necessarily mean that the end of the “ice age” (cryopreservation) is near.