IFI = invasive fungal infections. What is that? A misnomer, because a non-invasive fungal infection does not exist!

IFI = invasive fungal infections. What is that? A misnomer, because a non-invasive fungal infection does not exist!
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DOI:
10.1016/j.ijid.2009.08.006
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发表时间:
2010-06-01
影响因子:
8.4
通讯作者:
Hof, Herbert
Hof, Herbert
中科院分区:
医学2区
文献类型:
--
作者:
Hof, Herbert

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原则上,人们必须区分单纯的定植和侵袭性真菌感染(IFI),其临床表现和后果完全不同。如果侵袭性一词在其正确的意义上使用(expressis verbis),所有的真菌感染都可以被称为侵袭性,甚至真菌性角膜炎或皮肤真菌引起的毛发感染。然而,一般而言,IFI一词仅用于表征全身性、全身性、深层、内脏和严重的、危及生命的真菌感染,而非浅表性、局部性、良性、自限性真菌疾病。因此,通常使用的术语IFI具有误导性,令人困惑,并且根本无助于正确区分轻度,中度和重度真菌感染。(C)2009年国际传染病学会。由爱思唯尔有限公司出版。保留所有权利。
In principle, one has to differentiate between a mere colonization and an invasive fungal infection (IFI) with quite different clinical manifestations and consequences. If the term invasive were used in its proper sense (expressis verbis), all fungal infections could be called invasive, even a fungal keratitis or an infection of the hairs by dermatophytes. In general, however, the term IFI is used only to characterize systemic, generalized, deep-seated, visceral and severe, life-threatening fungal infections, in contrast to superficial, local, benign, self-limiting fungal diseases. The term IFI as used generally is thus misleading, confusing, and not at all helpful to correctly differentiate mild, moderate, and severe fungal infections. (C) 2009 International Society for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.