Who Needs to Be Targeted for HIV Testing and Treatment in KwaZulu-Natal? Results From a Population-Based Survey

Who Needs to Be Targeted for HIV Testing and Treatment in KwaZulu-Natal? Results From a Population-Based Survey
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DOI:
10.1097/qai.0000000000001081
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发表时间:
2016-12-01
影响因子:
3.6
通讯作者:
Ellman, Tom
Ellman, Tom
中科院分区:
医学3区
文献类型:
--
作者:
Huerga, Helena;Van Cutsem, Gilles;Ellman, Tom

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导言:确定艾滋病毒检测和治疗方面的差距对于针对无法获得艾滋病毒服务的人制定具体战略至关重要。我们评估的患病率和相关因素是艾滋病毒未经检测,不知情,未经治疗,病毒未抑制在夸祖鲁-纳塔尔,南非。方法:横断面人口为基础的调查。年龄在15-59岁之间的人有资格参加。访谈,HIV检测,抗逆转录病毒药物存在测试,CD 4和病毒载量的血液采集在参与者的home.Results:包括5649人,81.4%(95%CI:79.8至82.9)以前进行了测试。艾滋病毒感染率为25.2%。HIV阳性知晓率为75.2%(95%CI:72.9 ~ 77.4)。在所有不知情者中,73.3%的人年龄在35岁,68.7%为妇女。在符合治疗条件的人(CD 4 < 350,PMTCT-B)中,抗逆转录病毒治疗覆盖率为75.0%(95%CI:72.0至77.8),在所有艾滋病毒阳性者中为53.1%(95%CI:50.4至55.7)。病毒载量= 1000拷贝/毫升的人年龄,35岁和女性分别,男性有4.4,1.8,1.6和1.7倍的几率被未经测试,不知情,未经治疗,和病毒未抑制。此外,有1个以上性伴侣的人未检测、未意识到和未治疗的几率分别为1.3、2.2和1.9倍。结论:大多数不知道自己状况、未治疗和病毒未抑制的HIV阳性者是年龄较大的人。
Introduction: Identifying gaps in HIV testing and treatment is essential to design specific strategies targeting those not accessing HIV services. We assessed the prevalence and factors associated with being HIV untested, unaware, untreated, and virally unsuppressed in KwaZulu-Natal, South Africa.Methods: Cross-sectional population-based survey. People aged 15-59 years were eligible. Interviews, HIV testing, and blood collection for antiretroviral drug presence test, CD4, and viral load were done at the participants' home.Results: Of the 5649 individuals included, 81.4% (95% CI: 79.8 to 82.9) had previously been tested. HIV prevalence was 25.2%. HIV-positivity awareness rate was 75.2% (95% CI: 72.9 to 77.4). Of all unaware, 73.3% of people were aged,35 years and 68.7% were women. Antiretroviral therapy coverage was 75.0% (95% CI: 72.0 to 77.8) among those eligible for treatment (CD4 < 350, PMTCT-B) and 53.1% (95% CI: 50.4 to 55.7) among all HIV-positive individuals. Viral load was = 1000 copies per milliliter were people aged,35 years and women respectively, men had 4.4, 1.8, 1.6, and 1.7 times the odds of being untested, unaware, untreated, and virally unsuppressed. In addition, people with more than 1 sexual partner had 1.3, 2.2, and 1.9 times the odds of being untested, unaware, and untreated.Conclusions: The majority of HIV-positive people unaware of their status, untreated, and virally unsuppressed were individuals aged