Pathologic human GR mutant has a transdominant negative effect on the wild-type GR by inhibiting its translocation into the nucleus: importance of the ligand-binding domain for intracellular GR trafficking.
Pathologic human GR mutant has a transdominant negative effect on the wild-type GR by inhibiting its translocation into the nucleus: importance of the ligand-binding domain for intracellular GR trafficking.
复制标题
病理性人类 GR 突变体通过抑制野生型 GR 易位到细胞核中,对野生型 GR 产生显性负面影响:配体结合结构域对于细胞内 GR 运输的重要性。
DOI:
10.1210/jcem.86.11.8017
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发表时间:
2001
期刊:
影响因子:
--
通讯作者:
Chrousos,GP
中科院分区:
文献类型:
--
作者:
Kino,T;Stauber,RH;Resau,JH;Pavlakis,GN;Chrousos,GP