Cortical excitability and recovery curve analysis in generalized epilepsy
Cortical excitability and recovery curve analysis in generalized epilepsy
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DOI：
10.1212/wnl.53.6.1347
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发表时间：
1999-10-12
期刊：
影响因子：
9.9
通讯作者：
Berkovic, SF
中科院分区：
文献类型：
--
作者：
Brodtmann, A;Macdonell, RAL;Berkovic, SF
Seven untreated patients with idiopathic generalized epilepsy were studied with recovery curve analysis using transcranial magnetic stimulation and compared with 16 controls. Patients had a shorter period of inhibition of the test response following a conditioning stimulus and demonstrated a period of increased facilitation of the test response at interstimulus intervals of 200 to 300 msec, which was similar to the mean interdischarge interval of spike-wave activity on EEG. This provides further evidence of cortical hyperexcitability in idiopathic generalized epilepsy.
