Core-sheath polymer nanofiber formation by the simultaneous application of rotation and pressure in a novel purpose-designed vessel
Core-sheath polymer nanofiber formation by the simultaneous application of rotation and pressure in a novel purpose-designed vessel
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DOI：
10.1063/5.0071257
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发表时间：
2021-12-01
影响因子：
15
通讯作者：
Edirisinghe, Mohan
中科院分区：
文献类型：
--
作者：
Alenezi, Hussain;Cam, Muhammet Emin;Edirisinghe, Mohan
形成聚合物核心-鞘纳米纤维因其众多的潜在应用而日益突出，最显著的是在抗病毒过滤等功能场景中，由于目前的冠状病毒大流行，这引起了极大的关注。本研究成功地设计并建造了一种新型的加压回转容器来制备核-鞘聚合物纳米纤维。研究了几种水溶性和不溶于水的聚合物组合。分别以聚环氧乙烷和聚乙烯醇为芯材，聚乳酸和聚己内酯为鞘，分别以聚乳酸和聚己内酯为芯材和鞘。采用计算流体力学方法模拟了容器内的芯鞘流动，研究了有压和无压情况下容器内芯套的流体行为。使用高速摄像机观察了芯鞘开口处喷射溶液的行为，当旋转速度为6000转/分，施加0.2兆帕(两倍大气压)的压力时，获得了最佳方案。用扫描电子显微镜研究了芯鞘纤维的表面形貌，用聚焦离子束研磨辅助扫描电子显微镜研究了所制得纤维的横截面特征。用激光共聚焦扫描显微镜对纤维的芯鞘结构进行了验证，并用傅立叶变换红外光谱和差示扫描量热仪对其进行了表征。因此，使用各种聚合物组合，我们在理论和实验上展示了芯鞘纤维如何在容器中演变，该容器可以作为可扩展的制造加压回转生产过程。
Forming polymeric core-sheath nanofibers is gaining prominence owing to their numerous potential applications, most notably in functional scenarios such as antiviral filtration, which is attracting significant attention due to the current COVID pandemic. This study has successfully designed and constructed a novel pressurized gyration vessel to fabricate core-sheath polymer nanofibers. Several water-soluble and water-insoluble polymer combinations are investigated. Both polyethylene oxide and polyvinyl alcohol were used as the core while both poly(lactic acid) (PLA) and poly(caprolactone) (PCL) were used as the sheath; PLA and PCL were used as core and sheath, in different instances; respectively. The fluid behavior of the core-sheath within the vessel was studied with and without applied pressure using computational fluid dynamics to simulate the core-sheath flow within the chamber. A high-speed camera was used to observe the behavior of jetted solutions at core-sheath openings, and the best scenario was achieved using 6000 rpm spinning speed with 0.2 MPa (twice atmospheric) applied pressure. The surface morphology of core-sheath fibers was studied using a scanning electron microscope, and focused ion beam milling assisted scanning electron microscopy was used to investigate the cross-sectional features of the produced fibers. Laser confocal scanning microscopy was also used to verify the core-sheath structure of the fibers, which were further characterized by Fourier transform infrared spectroscopy and differential scanning calorimetry. Thus, using a variety of polymer combinations, we show, both theoretically and experimentally, how core-sheath fibers evolve in a vessel that can serve as a scalable manufacturing pressurized gyration production process.