Visual dysfunction following blast-related traumatic brain injury from the battlefield
Visual dysfunction following blast-related traumatic brain injury from the battlefield
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DOI：
10.3109/02699052.2010.536195
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发表时间：
2011-01-01
期刊：
影响因子：
1.9
通讯作者：
Galarneau, Michael R.
中科院分区：
文献类型：
--
作者：
Dougherty, Amber L.;MacGregor, Andrew J.;Galarneau, Michael R.
主要目的：评估伊拉克自由行动中爆炸相关脑损伤(TBI)后眼部和视觉障碍的发生情况。研究设计：回顾性队列研究。方法和步骤：从远征医疗遭遇数据库中确定2254名患有爆炸相关战伤的美国军人进行分析。使用伤点附近的病历信息来评估与伤后12个月内诊断眼/视力障碍相关的因素，包括颅脑损伤的严重程度。主要结果与结果：在2254名现役军人中，837人(37.1%)遭受了爆炸伤，1417人(62.9%)有其他爆炸伤。201例(8.9%)在冲击伤后12个月内被诊断为眼部或视力障碍。与其他损伤的军人相比，中度颅脑损伤(优势比OR=1.58，95%可信区间(CI)=1.02~2.45)和重型至重型颅脑损伤(OR=14.26，95%CI=7.00~29.07)的眼/视功能障碍的发生几率显著增加。结论：冲击性脑损伤与伤后1年内的视功能障碍密切相关，且随着颅脑损伤程度的加重，眼/视功能障碍的发生率呈上升趋势。在战区接受颅脑损伤后，可能需要进行全面的视力检查。
Primary objective: To assess the occurrence of ocular and visual disorders following blast-related traumatic brain injury (TBI) in Operation Iraqi Freedom.Research design: Retrospective cohort study.Methods and procedures: A total of 2254 US service members with blast-related combat injuries were identified for analysis from the Expeditionary Medical Encounter Database. Medical record information near the point of injury was used to assess factors associated with the diagnosis of ocular/visual disorder within 12 months after injury, including severity of TBI. Main outcomes and results: Of 2254 service members, 837 (37.1%) suffered a blast-related TBI and 1417 (62.9%) had other blast-related injuries. Two-hundred and one (8.9%) were diagnosed with an ocular or visual disorder within 12 months after blast injury. Compared with service members with other injuries, odds of ocular/visual disorder were significantly higher for service members with moderate TBI (odds ratio (OR) = 1.58, 95% confidence interval (CI) = 1.02-2.45) and serious to critical TBI (OR = 14.26, 95% CI = 7.00-29.07).Conclusions: Blast-related TBI is strongly associated with visual dysfunction within 1 year after injury and the odds of disorder appears to increase with severity of brain injury. Comprehensive vision examinations following TBI in theatre may be necessary.