Plasma and urinary follicle-stimulating hormone levels in oligospermia.
Plasma and urinary follicle-stimulating hormone levels in oligospermia.
复制标题
少精子症的血浆和尿卵泡刺激激素水平。
DOI：
--
复制
发表时间：
1972
影响因子：
5.8
通讯作者：
C. Paulsen
中科院分区：
文献类型：
--
作者：
J. Leonard;R. Leach;M. Couture;C. Paulsen
测定了少精症或无精症成年男性的血浆和尿液卵泡刺激素水平。排除血浆LH水平升高的患者。60例少精患者血浆FSH平均浓度（415±175 SD ng LER 907/ml）与42例正常生精对照组（355±76）比较，差异无统计学意义。只有无精子患者血浆FSH均匀升高（865±380）。精子数量与血浆FSH之间无直接的负相关关系（r = - 0.18, p > 0.10）。在另外12例少精子男性中，将睾丸活检标本的定量组织学特征与尿FSH水平进行比较。生发细胞数量与FSH滴度之间没有相关性。这些数据不支持生精活性和卵泡刺激素分泌之间直接相互关系的论点，但表明存在一个“独立的睾丸站”，但尚不清楚是哪个控制卵泡刺激素。
Plasma and urinary FSH levels were measured in adult men with oligospermia or azoospermia. Patients with elevated plasma LH levels were excluded. In 60 oligospermic subjects the mean plasma FSH concentration (415 ± 175 SD ng LER 907/ml) was not significantly higher than that of 42 control subjects with normal spermatogenesis (355 ± 76). Only in the azoospermic patients was the plasma FSH uniformally elevated (865 ± 380). No direct reciprocal relationship between sperm count and plasma FSH was evident in the oligospermic group (r = −0.18, p > 0.10). In 12 additional oligospermic men the quantitative histologic characteristics of testicular biopsy specimens were compared with urinary FSH levels. There was no correlation between the germinal cell populations and FSH titers. These data do not support the thesis of a direct reciprocal relationship between spermato-genic activity and FSH secretion but suggest the presence of an “independent testicular station,” yet undefined which controls FSH.