Near‐IR Fluorescent Recognition of Arginine: High Chemoselectivity and Enantioselectivity Promoted by La 3+
Near‐IR Fluorescent Recognition of Arginine: High Chemoselectivity and Enantioselectivity Promoted by La 3+
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精氨酸的近红外荧光识别：La 3 促进的高化学选择性和对映选择性
DOI：
10.1002/cplu.202300138
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发表时间：
2023
期刊：
影响因子：
3.4
通讯作者：
Pu, Lin
中科院分区：
文献类型：
--
作者：
Guo, Hongyu;Yang, Jiaqiao;Zeng, Jian;Yu, Xiaoqi;Yu, Shanshan;Pu, Lin
本文报道了第一个用于精氨酸在水溶液中的化学选择性和对映选择性识别的近红外荧光探针。该探针由1，1 '-联萘基手性醛单元和罗丹明基近红外发色团组成，与La 3+结合后，在λ=690 nm激发下，在λ=764 nm处对精氨酸表现出高度的化学选择性和对映选择性荧光增强。 对于手性不匹配的精氨酸对映体或其他常见氨基酸及其对映体，观察到很少或没有荧光响应。该探针还允许视觉辨别精氨酸对映体，因为其在与底物相互作用后快速且独特的颜色变化。
The first near IR fluorescent probe for the chemoselective and enantioselective recognition of arginine in aqueous solution is reported in this work. This probe, made of a 1,1’‐binaphthyl‐based chiral aldehyde unit and a rhodamine‐based near IR chromophore, in combination with La3+exhibits highly chemoselective as well as enantioselective fluorescent enhancement with arginine at λ=764 nm upon excitation at λ=690 nm. Little or no fluorescent response is observed toward the chirality miss‐matched arginine enantiomer or other common amino acids and their enantiomers. This probe also allows visual discrimination of the arginine enantiomers because of its fast and distinct color change upon interaction with the substrate.