Motivated to do well: An examination of the relationships between motivation, effort, and cognitive performance in schizophrenia
Motivated to do well: An examination of the relationships between motivation, effort, and cognitive performance in schizophrenia
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DOI：
10.1016/j.schres.2015.05.019
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发表时间：
2015-08-01
影响因子：
4.5
通讯作者：
Remington, G.
中科院分区：
文献类型：
--
作者：
Foussias, G.;Siddiqui, I.;Remington, G.
精神分裂症的阴性症状（特别是动机缺陷）与认知功能障碍之间的不确定关系需要进一步阐明，因为它涉及认知测试结果的解释。迄今为止的研究结果表明，动机缺陷对认知测试测量可能具有中介作用，尽管使用绩效有效性测量对努力进行正式检查的结果并不一致。本研究的目的是探讨精神分裂症患者在认知测试中的动机、努力程度和认知表现之间的关系。对 69 名患有精神分裂症或分裂情感障碍的门诊患者进行了精神病理学、动机缺陷的严重程度、认知测试期间的努力程度以及认知表现的评估。认知测试期间的动机和努力程度与认知表现显着相关，特别是言语流畅性、言语和工作记忆、注意力和处理速度以及推理和解决问题的能力。此外，努力程度占认知表现差异的 15%，并且部分调节了动机和认知表现之间的关系。检查正常或减少努力的个体的认知表现概况，发现整体认知、注意力/处理速度、推理和解决问题的显着差异。这些发现表明，认知领域可能会受到动机和努力受损的不同影响，并强调了了解动机和认知表现缺陷之间相互作用的重要性，这可能指导适当选择症状目标以促进患者康复。 (C) 2015 Elsevier B.V. 保留所有权利。
The uncertain relationship between negative symptoms, and specifically motivational deficits, with cognitive dysfunction in schizophrenia is in need of further elucidation as it pertains to the interpretation of cognitive test results. Findings to date have suggested a possible mediating role of motivational deficits on cognitive test measures, although findings from formal examinations of effort using performance validity measures have been inconsistent. The aim of this study was to examine the relationships between motivation, effort exerted during cognitive testing, and cognitive performance in schizophrenia. Sixty-nine outpatients with schizophrenia or schizoaffective disorder were evaluated for psychopathology, severity of motivational deficits, effort exerted during cognitive testing, and cognitive performance. Motivation and degree of effort exerted during cognitive testing were significantly related to cognitive performance, specifically verbal fluency, verbal and working memory, attention and processing speed, and reasoning and problem solving. Further, effort accounted for 15% of the variance in cognitive performance, and partially mediated the relationship between motivation and cognitive performance. Examining cognitive performance profiles for individuals exerting normal or reduced effort revealed significant differences in global cognition, as well as attention/processing speed and reasoning and problem solving. These findings suggest that cognitive domains may be differentially affected by impairments in motivation and effort, and highlight the importance of understanding the interplay between motivation and cognitive performance deficits, which may guide the appropriate selection of symptom targets for promoting recovery in patients. (C) 2015 Elsevier B.V. All rights reserved.