Microfluidic synthesis of colloidal silica
Microfluidic synthesis of colloidal silica
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DOI：
10.1021/la0499012
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发表时间：
2004-09-28
期刊：
影响因子：
3.9
通讯作者：
Jensen, KF
中科院分区：
文献类型：
--
作者：
Khan, SA;Günther, A;Jensen, KF
我们展示了用于合成胶体二氧化硅颗粒的微流控化学反应器的设计、制造和操作。两个反应器配置检查：层流反应器和分段流反应器。我们分析了颗粒的尺寸和尺寸分布，并研究它们随不同的线性流速和平均停留时间的变化。层流反应器在高线速度下受到轴向分散的影响，因此在这些条件下导致宽的粒度分布。气体用于产生分段流，由惰性气体气泡分隔的液体塞组成。在液体塞中产生的内部再循环产生混合，这消除了与层流反应器相关的轴向分散效应，并产生窄尺寸分布的二氧化硅纳米颗粒。
We demonstrate the design, fabrication, and operation of microfluidic chemical reactors for the synthesis of colloidal silica particles. Two reactor configurations are examined: laminar flow reactors and segmented flow reactors. We analyze particle sizes and size distributions and examine their change with varying linear flow velocity and mean residence time. Laminar flow reactors are affected by axial dispersion at high linear velocities, thus leading to wide particle size distributions under these conditions. Gas is used to create a segmented flow, consisting liquid plugs separated by inert gas bubbles. The internal recirculation created in the liquid plugs generates mixing, which eliminates the axial dispersion effects associated with laminar flow reactors and produces a narrow size distribution of silica nanoparticles.