FDT Perimetry for Glaucoma Detection in Comprehensive Health Checkup Service
FDT Perimetry for Glaucoma Detection in Comprehensive Health Checkup Service
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DOI：
10.1155/2020/4687398
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发表时间：
2020-04-01
影响因子：
1.9
通讯作者：
Nakano, Tadashi
中科院分区：
文献类型：
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作者：
Terauchi, Ryo;Wada, Takashi;Nakano, Tadashi
我们的目的是探讨倍频技术（FDT）视野检查在青光眼综合筛查检查中的有效性。我们对前瞻性收集的接受全面健康检查服务的参与者的数据进行了回顾性分析。排除青光眼患者。在第一年，2024名接受FDT视野检查和眼底照相的参与者（46.8 +/- 9.4岁）被归类为FDT组，而3052名仅接受眼底照相的参与者（42.2 +/- 8.2岁）被归类为非FDT对照组。FDT视野检查和/或眼底照相结果异常的受试者建议接受进一步的全面检查。所有参与者报告他们是否在首次就诊后2年内被新诊断为青光眼。在FDT组中，23名（1.14%）参与者被新诊断为青光眼。其中FDT视野检查异常20例（87.0%），眼底照相异常12例（52.2%）。FDT视野检查阳性预测值为16.5%（20/121），眼底照相阳性预测值为13.3%（12/90）。在两项测试均异常的参与者中，PPV为26.2%。在非FDT组中，15名（0.49%）参与者新诊断为青光眼。其中9例（60.0%）眼底照相异常。眼底照相阳性预测值为10.8%（9/83）。采用年龄校正分析，FDT组的青光眼检出率显著高于非FDT组（0.97% vs 0.47%，P=0.041）。FDT视野检查，即使由非专业医生进行，也可以提高青光眼的检测，当除了眼底照相。本研究已在UMIN 000037951中注册。
We aimed to investigate the efficacy of frequency doubling technology (FDT) perimetry for glaucoma detection in comprehensive screening examinations. We performed a retrospective analysis of prospectively collected data of participants who underwent a comprehensive health checkup service. Participants with glaucoma were excluded. In the first year, 2024 participants (46.8 +/- 9.4 years) who underwent FDT perimetry and fundus photography were classified as the FDT group, whereas 3052 participants (42.2 +/- 8.2 years) who underwent only fundus photography were classified as the non-FDT control group. Participants with abnormal findings on FDT perimetry and/or fundus photography were recommended to undergo further complete examination. All participants reported whether they had been newly diagnosed with glaucoma within 2 years of the first visit. In the FDT group, 23 (1.14%) participants were newly diagnosed with glaucoma. Among them, 20 (87.0%) had abnormal FDT perimetry findings and 12 (52.2%) had abnormal findings on fundus photography. The positive-predictive value (PPV) of FDT perimetry was 16.5% (20/121) and that of fundus photography was 13.3% (12/90). In participants with abnormal findings on both tests, the PPV was 26.2%. In the non-FDT group, 15 (0.49%) participants were newly diagnosed with glaucoma. Among them, 9 (60.0%) had abnormal findings on fundus photography. The PPV of fundus photography was 10.8% (9/83). The glaucoma detection rate, analyzed using age adjustment, was significantly higher in the FDT group than that in the non-FDT group (0.97% versus 0.47%, P=0.041). FDT perimetry, even if performed by nonspecialized physicians, could improve glaucoma detection when used in addition to fundus photography. This study was registered with UMIN000037951.