A Ligand-Free Copper-Catalyzed Decarboxylative Trifluoromethylation of Aryliodides with Sodium Trifluoroacetate Using Ag2O as a Promoter
A Ligand-Free Copper-Catalyzed Decarboxylative Trifluoromethylation of Aryliodides with Sodium Trifluoroacetate Using Ag2O as a Promoter
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Ag2O 为促进剂的无配体铜催化芳基碘化物与三氟乙酸钠的脱羧三氟甲基化
DOI：
10.1055/s-0030-1260930
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发表时间：
2011-07-01
期刊：
影响因子：
2
通讯作者：
Duan, Chunying
中科院分区：
文献类型：
--
作者：
Li, Yaming;Chen, Tao;Duan, Chunying
报道了一种无配体的铜催化芳基碘与三氟乙酸钠的脱羧三氟甲基化反应。在相对温和的反应条件下，以中等至优异的产率合成了各种三氟甲基取代的芳族化合物，并且具有宽的官能团耐受性。
A practical and ligand-free Cu-catalyzed decarboxylative trifluoromethylation of aryl iodides with sodium trifluoroacetate using Ag 2 O as a promoter was reported. A variety of trifluoromethyl-substituted aromatics are synthesized in moderate to excellent yields and with wide functional-group tolerance under relatively mild reaction conditions.