IgG gene expression and its possible significance in prostate cancers
IgG gene expression and its possible significance in prostate cancers
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IgG 基因表达及其在前列腺癌中的可能意义
DOI：
10.1002/pros.21476
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发表时间：
2012-05-01
期刊：
影响因子：
2.8
通讯作者：
Gu, Jiang
中科院分区：
文献类型：
--
作者：
Liu, Yuxuan;Chen, Zhengshan;Gu, Jiang
尽管最近在治疗策略方面取得了进展，但前列腺癌（PCa）仍然是男性癌症死亡的第二大原因，其遗传和生物学行为仍然知之甚少。近年来，越来越多的证据表明，癌细胞以及一些正常细胞可以分泌IgG。本研究旨在评估IgG基因在PCa组织样品和细胞系中的表达及其可能的意义。
In spite of recent advances in treatment strategies, prostate cancer (PCa) remains the second leading cause of cancer death in men with its genetic and biologic behaviors still poorly understood. Recently, accumulating evidence indicates that cancer cells, as well as some normal cells can secret IgG. This study was designed to evaluate IgG gene expression and its possible significance in PCa tissue samples and cell lines.