Novel synthesis of 5-iodo-1,2,3-triazoles using an aqueous iodination system under air
Novel synthesis of 5-iodo-1,2,3-triazoles using an aqueous iodination system under air
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空气下水性碘化系统新合成 5-碘-1,2,3-三唑
DOI：
10.1016/j.tetlet.2018.08.039
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发表时间：
2018-09-26
影响因子：
1.8
通讯作者：
Zhang, Guisheng
中科院分区：
文献类型：
--
作者：
Li, Lingjun;Xing, Xiaofang;Zhang, Guisheng
提出了一种新的水相碘化反应体系，用于在空气中合成5-碘-1，2，3-三唑。该反应体系具有反应效率高、化学选择性好、官能团耐受性广等特点。此外，该方法可用于修饰生物分子如核糖和核苷，以及当与其他反应类型如Sonogashira反应偶联时用于生物分子的双标记。(C)2018爱思唯尔有限公司版权所有
A novel aqueous iodination system was developed for the synthesis of 5-iodo-1,2,3-triazoles under air. This reaction system has high efficiency and excellent chemo-selectivity with wide functional group tolerance. In addition, this method can be utilized for the modification of biomolecules such as riboses and nucleosides, and for the double labeling of biomolecules when coupled with other reaction types such as the Sonogashira reaction. (C) 2018 Elsevier Ltd. All rights reserved.