Targeted secretion: Myosin V delivers vesicles through formin condensates.
Targeted secretion: Myosin V delivers vesicles through formin condensates.
复制标题
定向分泌：肌球蛋白 V 通过福尔明冷凝物递送囊泡。
DOI：
10.1016/j.cub.2022.10.001
复制
发表时间：
2022
期刊：
影响因子：
--
通讯作者：
Lew,DanielJ
中科院分区：
文献类型：
--
作者：
Jacobs,KatherineC;Gladfelter,AmyS;Lew,DanielJ
分泌囊泡通常被递送到非常特定的靶点，如突触前末梢或细胞尖端，以集中胞吐作用。新的工作表明，生物分子凝聚物集中肌动蛋白丝，通过凝聚物将传入的囊泡传递到质膜。
Secretory vesicles are often delivered to very specific targets, like pre-synaptic terminals or cell tips, to focus exocytosis. New work suggests that a biomolecular condensate focuses actin filaments that deliver incoming vesicles through the condensate to the plasma membrane.