Taenia solium taeniasis and cysticercosis control and elimination through community-based interventions.
Taenia solium taeniasis and cysticercosis control and elimination through community-based interventions.
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DOI：
10.1007/s40475-014-0029-4
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发表时间：
2014-12-01
影响因子：
5.4
通讯作者：
中科院分区：
文献类型：
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1992年，国际消灭疾病工作队宣布猪带绦虫有可能被根除。然而，很少有设计良好的社区为基础的随机对照试验已经进行了衡量替代控制策略的有效性。大多数战略都在极少数社区的前后干预设计中进行了测试，通常没有对照组。仅有的两项以社区为基础的随机对照试验表明，单独的教育计划或人类和猪群治疗的组合在短期内减少了猪囊虫病。传播动力学模型表明，改善卫生和猪管理比猪疫苗接种、人或猪群治疗更有效和可持续。目前的证据不支持在可预见的将来消灭猪带绦虫。研究者应遵循国际上关于开展以社区为基础的随机对照试验的建议，以提供对囊虫病替代控制策略的效果和成本效益的更有效估计。
Taenia solium was declared potentially eradicable by the International Task Force for Disease Eradication in 1992. Yet, very few well-designed community-based randomized controlled trials have been conducted to measure the effectiveness of alternative control strategies. Most strategies have been tested in pre-post intervention designs in very few communities, often without a control group. The only two community-based randomized controlled trials suggest that an educational program alone or a combination of human and porcine mass treatment reduce porcine cysticercosis in the short term. A transmission dynamics model suggests that improved sanitation and pig management are more effective and sustainable than pig vaccination, human or porcine mass treatment. Current evidence does not support the eradication of Taenia solium in the foreseeable future. Investigators should follow international recommendations on the conduct of community-based randomized control trials to provide more valid estimates of the effect and cost-effectiveness of alternative control strategies for cysticercosis.