Dendritic structure and receptive-field organization of optic flow processing interneurons in the fly
Dendritic structure and receptive-field organization of optic flow processing interneurons in the fly
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DOI：
10.1152/jn.1998.79.4.1902
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发表时间：
1998-04-01
影响因子：
2.5
通讯作者：
Hengstenberg, R
中科院分区：
文献类型：
--
作者：
Krapp, HG;Hengstenberg, B;Hengstenberg, R
红头丽蝇的第三视神经节（小叶板）是处理运动信息的中心。其中，IO包含10个可单独识别的“垂直系统”（VS）神经元，对任意模式的视觉宽场运动做出响应。我们证明，每个VS神经元被调谐到感测在自运动过程中产生的光流的特定方面。因此，果蝇的VS神经元为控制头部方向、身体姿势和飞行方向提供视觉信息。为了揭示10个VS神经元感受野的功能组织，我们用一种新的方法确定了苍蝇视野中52个位置的局部运动敏感性和局部优选方向的分布。通过荧光黄细胞内染色和10 μ m连续切片的三维重建来鉴定每个神经元。因此，每个记录的神经元的感受野组织可以与其树突状分支的位置和程度的视网膜定位组织的神经节的小叶板。VS神经元的响应场，即，局部优选方向和局部运动灵敏度的分布不是均匀的，而是类似于在围绕各个水平轴旋转期间由苍蝇引起的旋转光流场。理论上的考虑和定量分析的数据，这将在随后的论文中提出，表明VS神经元是高度专业化的神经过滤器的光流处理，从而为在飞的自我运动的视觉感觉。
The third visual neuropil (lobula plate) of the blowfly Calliphora erythrocephala is a center for processing motion information. Io contains, among others, 10 individually identifiable "vertical system" (VS) neurons responding to visual wide-field motions of arbitrary patterns. We demonstrate that each VS neuron is tuned to sense a particular aspect of optic flow that is generated during self-motion. Thus the VS neurons in the fly supply visual information for the control of head orientation, body posture, and flight steering. To reveal the functional organization of the receptive fields of the 10 VS neurons, we determined with a new method the distributions of local motion sensitivities and local preferred directions at 52 positions in the fly's visual field. Each neuron was identified by intracellular staining with Lucifer yellow and three-dimensional reconstructions from 10-mu m serial sections. Thereby the receptive-field organization of each recorded neuron could be correlated with the location and extent of its dendritic arborization in the retinotopically organized neuropil of the lobula plate. The response fields of the VS neurons, i.e., the distributions of local preferred directions and local motion sensitivities, are not uniform but resemble rotatory optic flow fields that would be induced by the fly during rotations around various horizontal axes. Theoretical considerations and quantitative analyses of the data, which will be presented in a subsequent paper, show that VS neurons are highly specialized neural filters for optic flow processing and thus for the visual sensation of self-motions in the fly.