Mucosa-associated lymphoid tissue lymphoma studied with FDG-PET: a comparison with CT and endoscopic findings
Mucosa-associated lymphoid tissue lymphoma studied with FDG-PET: a comparison with CT and endoscopic findings
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DOI：
10.1007/s12149-007-0125-9
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发表时间：
2008-05-01
影响因子：
2.6
通讯作者：
Hatazawa, Jun
中科院分区：
文献类型：
--
作者：
Enomoto, Keisuke;Hamada, Kenichiro;Hatazawa, Jun
目的探讨2-脱氧-2-[F-18]-D-葡萄糖正电子发射断层扫描（FDG-PET）在粘膜相关淋巴组织（MALT）淋巴瘤中的积聚情况，并与CT和内镜成像进行比较。所有患者均行病灶CT扫描，并与FDG-PET图像进行比较。结果13例未经治疗的胃MALT淋巴瘤患者中，8例非胃MALT淋巴瘤患者均出现FDG异常积聚。然而，在5例胃MALT淋巴瘤患者中，未观察到异常FDG蓄积。结论胃MALT淋巴瘤形成肿块时，FDG-PET可检出MALT淋巴瘤，而胃MALT淋巴瘤形成肿块时，FDG-PET难以检出胃肠道来源的非肿块型MALT淋巴瘤。
Objective We investigated the accumulation of 2-deoxy-2-[F-18] fluoro-D-glucose positron emission tomography (FDG-PET) in patients with mucosa-associated lymphoid tissue (MALT) lymphoma patients as compared with computerized tomography (CT) and endoscopic imaging.Methods FDG-PET was performed on 13 untreated patients with MALT lymphoma. CT scanning of the affected areas was performed in all the patients to compare with the FDG-PET images. In five patients with gastric MALT lymphoma, comparison was also made with the endoscopic findings.Results Of the 13 untreated MALT lymphoma patients, all 8 non-gastric MALT lymphoma patients exhibited abnormal accumulation of FDG. However, in the five gastric MALT lymphoma patients, no abnormal FDG accumulation was observed. Although lesions could be confirmed on CT images from the patients other than those with gastric MALT lymphoma, the mucosal lesions of gastric MALT lymphoma could be observed only by endoscopy.Conclusions FDG-PET can be used to detect MALT lymphoma when it forms mass lesions, whereas it is difficult to detect non-massive MALT lymphoma of gastrointestinal origin.