Behavioral genetics and taste.
Behavioral genetics and taste.
复制标题
行为遗传学和品味。
DOI：
10.1186/1471-2202-8-s3-s3
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发表时间：
2007-09-18
期刊：
影响因子：
2.4
通讯作者：
Bachmanov, Alexander A.
中科院分区：
文献类型：
--
作者：
Boughter, John D., Jr.;Bachmanov, Alexander A.
本文综述了哺乳动物对甜味、鲜味、苦味和盐味反应的行为遗传学研究。讨论了涉及小鼠近交系比较和遗传分析的研究，以及它们对阐明味觉受体和转导机制的影响。最后，我们考虑了味觉反应的遗传变异对药物摄入量等复杂性状的影响。基因组资源开发的最新进展使行为遗传学成为理解味觉机制的有力途径。
This review focuses on behavioral genetic studies of sweet, umami, bitter and salt taste responses in mammals. Studies involving mouse inbred strain comparisons and genetic analyses, and their impact on elucidation of taste receptors and transduction mechanisms are discussed. Finally, the effect of genetic variation in taste responsiveness on complex traits such as drug intake is considered. Recent advances in development of genomic resources make behavioral genetics a powerful approach for understanding mechanisms of taste.