High-Rate Internal Pressurization of Human Eyes to Predict Globe Rupture
High-Rate Internal Pressurization of Human Eyes to Predict Globe Rupture
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DOI：
10.1001/archophthalmol.2008.614
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发表时间：
2009-04-01
影响因子：
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通讯作者：
Duma, Stefan M.
中科院分区：
文献类型：
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作者：
Bisplinghoff, Jill A.;McNally, Craig;Duma, Stefan M.
目的：为了确定动态破裂压力的人的眼睛，通过使用体外高速率加压系统，调查钝性冲击eye injuries.Methods：内部压力动态引起的眼睛通过下降塔加压系统。通过视神经插入眼内的小型压力传感器测量眼内压。共进行了20人的眼睛测试，以确定破裂压力和破裂patterns.Results：高速率加压导致的平均（SD）破裂压力为0.97（0.29）MPa（7275.60 [2175.18] mm Hg）。共有16只眼在赤道方向破裂，而4只眼在赤道方向破裂。赤道和赤道方向之间的破裂压力没有显著差异（P=.16）。结论：随着负荷率的增加，人眼的破裂压力增加。临床相关性：眼损伤是昂贵的治疗，估计每年的费用与成人视力问题在美国是514亿美元。确定地球仪破裂特性将为人眼建立损伤标准，以防止这些常见但毁灭性的损伤。
Objective: To determine the dynamic rupture pressure of the human eye by using an in vitro high-rate pressurization system to investigate blunt-impact eye injuries.Methods: Internal pressure was dynamically induced in the eye by means of a drop-tower pressurization system. The internal eye pressure was measured with a small pressure sensor inserted into the eye through the optic nerve. A total of 20 human eye tests were performed to determine rupture pressure and characterize rupture patterns.Results: The high-rate pressurization resulted in a mean (SD) rupture pressure of 0.97 (0.29) MPa (7275.60 [2175.18] mm Hg). A total of 16 eyes ruptured in the equatorial direction, whereas 4 ruptured in the meridional direction. There was no significant difference in the rupture pressure between the equatorial and meridional directions (P=.16).Conclusion: As the loading rate increases, the rupture pressure of the human eye increases.Clinical Relevance: Eye injuries are expensive to treat, given that the estimated annual cost associated with adult vision problems in the United States is $51.4 billion. Determining globe rupture properties will establish injury criteria for the human eye to prevent these common yet devastating injuries.