Predictive, preventive, personalized and participatory medicine: back to the future.

Predictive, preventive, personalized and participatory medicine: back to the future.
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DOI:
10.1186/gm178
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发表时间:
2010-08-26
期刊:
影响因子:
12.3
通讯作者:
Hood L
Hood L
中科院分区:
生物学1区
文献类型:
--
作者:
Auffray C;Charron D;Hood L

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Jean Dausset关于人类白细胞抗原系统的开创性工作确立了几项原则,这些原则后来反映在人类基因组计划中,并为预测性、预防性、个性化和参与性医学(P4)奠定了基础。为了有效地发展系统医学,我们应该利用人类白细胞抗原事件的教训,强调探索一种迷人但神秘的生物学的重要性,现在使用系统原理,开拓新技术发展,创造共享的生物和信息资源。
The pioneering work of Jean Dausset on the HLA system established several principles that were later reflected in the Human Genome Project and contributed to the foundations of predictive, preventive, personalized and participatory (P4) medicine. To effectively develop systems medicine, we should take advantage of the lessons of the HLA saga, emphasizing the importance of exploring a fascinating but mysterious biology, now using systems principles, pioneering new technology developments and creating shared biological and information resources.
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