Development and Validation of a Nomogram for Predicting Albumin Transfusion After Spinal Tuberculosis Surgery: Based on Propensity Score Matching Analysis
Development and Validation of a Nomogram for Predicting Albumin Transfusion After Spinal Tuberculosis Surgery: Based on Propensity Score Matching Analysis
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DOI：
10.1016/j.wneu.2021.10.102
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发表时间：
2021-12-15
影响因子：
2
通讯作者：
Zhan, Xinli
中科院分区：
文献类型：
--
作者：
Chen, Liyi;Liu, Chong;Zhan, Xinli
- 背景：基于诺模图和倾向评分匹配（PSM）分析的应用，很少有文献报道使用围手术期参数预测脊柱结核手术后白蛋白输注的风险。目的：本研究旨在结合PSM和列线图预测脊柱结核手术后白蛋白输注的风险。- 方法：收集患者的临床资料，包括术前临床资料、术前实验室检查和术后临床资料。将所有资料分为白蛋白输注组和非白蛋白输注组。采用PSM分析调整2组基线数据。进一步构建诺模图。评价了模型的实用性和预测能力。结果：共收集到494例病例，经PSM分析得到102对病例，构建了列线图。Logistic分析显示，手术入路、谷草转氨酶/谷丙转氨酶水平、引流量和脊柱后凸存在统计学差异，这些参数均纳入诺模图的构建中。预测模型的C指数为0.734。曲线下面积为0.73，净效益在0.13和0.99之间。通过内部验证方法计算的C指数为0.71。结论：PSM分析具有良好的拟合效果，诺模图具有良好的预测能力。手术方式、谷草转氨酶/谷丙转氨酶水平、引流和脊柱后凸可能是脊柱结核手术后白蛋白输注的预测因素。
-BACKGROUND: There have been few literature reports on the use of perioperative parameters to predict the risk of albumin transfusion after spinal tuberculosis surgery based on the application of nomogram and propensity score matching (PSM) analysis. -OBJECTIVE: The purpose was to predict the risk of al-bumin transfusion after spinal tuberculosis surgery based on a combination of PSM and nomogram. -METHODS: The clinical data of the patients were collected in our hospital, including preoperative clinical data, preoperative laboratory tests, and postoperative clinical data. All data were divided into 2 groups, including the albumin transfusion group and the nonealbumin transfusion group. The PSM analysis was used to adjust the baseline data of the 2 groups. The nomogram was further constructed. The practicability and predictive ability of the model were evaluated. -RESULTS: A total of 494 cases were collected in this article; 102 pairs by PSM analysis were used to construct the nomogram. There were statistical differences in sur-gical approach, aspartate aminotransferase/alanine aminotransferase levels, drainage, and kyphosis by logistic analysis, and these parameters were included in the con-struction of the nomogram. The C-index of the prediction model was 0.734. The area under the curve was 0.73 and the net benefit was between 0.13 and 0.99. The calculated C-index was 0.71 by the internal verification method. -CONCLUSIONS: The PSM analysis had a good matching effect and the nomogram had a good predictive ability. Surgical approach, aspartate aminotransferase/alanine aminotransferase levels, drainage, and kyphosis might be predictors of albumin transfusion after spinal tuberculosis surgery.