DIELECTRIC-PROPERTIES OF BREAST-CARCINOMA AND THE SURROUNDING TISSUES

DIELECTRIC-PROPERTIES OF BREAST-CARCINOMA AND THE SURROUNDING TISSUES
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DOI:
10.1109/10.1374
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发表时间:
1988-04-01
影响因子:
4.6
通讯作者:
SWARUP, A
SWARUP, A
中科院分区:
工程技术2区
文献类型:
--
作者:
SUROWIEC, AJ;STUCHLY, SS;SWARUP, A

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测定浸润性乳腺癌及其周围组织的相对介电常数。实验在20 kHz至100 MHz的频率下进行,温度为37℃,使用自动网络分析仪和线端电容传感器。利用计算机程序对Cole-Cole介电参数进行曲线拟合计算。主要考虑三种组织:肿瘤中心部分、肿瘤周围组织和周围组织。在每个类别中,不同标本的电介质数据的大量分布表明肿瘤组织的结构和细胞不均匀性。但各类别介质弛豫时间和弛豫时间分布系数有一定的一致性。结果似乎表明,射频阻抗成像可以作为一种潜在的诊断方式用于检测人类乳腺癌
Relative permittivity of infiltrating breast carcinoma and the surrounding tissue was measured. The experiments were performed at frequencies from 20 kHz to 100 MHz at 37 degrees C using an automatic network analyzer and an end-of-the-line capacitive sensor. Cole-Cole dielectric parameters were calculated by curve fitting using a computer program. Three main categories of tissues were considered: the central part of the tumor, the tumor surrounding tissue, and the peripheral tissue. Within each category, the large spread of the dielectric data for different specimens suggests structural and cellular inhomogeneities of the tumor tissue. However, certain consistency has been found in the dielectric relaxation time and the coefficient of the distribution of the relaxation time within each category. The results seem to indicate that RF impedance imaging can potentially be used as a diagnostic modality for the detection of human breast carcinoma.<>