famCNV: copy number variant association for quantitative traits in families
famCNV: copy number variant association for quantitative traits in families
复制标题
DOI：
10.1093/bioinformatics/btr264
复制
发表时间：
2011-07-01
期刊：
影响因子：
5.8
通讯作者：
Falchi, Mario
中科院分区：
文献类型：
--
作者：
Eleftherohorinou, Hariklia;Andersson-Assarsson, Johanna C.;Falchi, Mario
一个程序包，使拷贝数变异（CNVs）与任意大小和复杂性的家族的定量表型全基因组关联。作为拷贝数代理的强度信号在方差组件框架中建模，并通过正式的似然测试评估与性状的关联。
A program package to enable genome-wide association of copy number variants (CNVs) with quantitative phenotypes in families of arbitrary size and complexity. Intensity signals that act as proxies for the number of copies are modeled in a variance component framework and association with traits is assessed through formal likelihood testing.