Direction-selective visual responses in macaque superior colliculus induced by behavioral training.
Direction-selective visual responses in macaque superior colliculus induced by behavioral training.
复制标题
行为训练诱导的猕猴上丘方向选择性视觉反应。
DOI：
10.1016/j.neulet.2004.05.059
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发表时间：
2004
期刊：
影响因子：
--
通讯作者：
Newsome,WilliamT
中科院分区：
文献类型：
--
作者：
Horwitz,GregoryD;Batista,AaronP;Newsome,WilliamT
在以前的报告中，我们描述了一个迄今未被发现的神经元群体的中间和深层的猴上级丘（SC），产生方向选择性视觉反应的刺激内的中央4°的视野。我们在三只猴子身上观察到了这些神经元，这些猴子经过了广泛的训练，在视野的这个区域执行视觉方向辨别任务。该任务要求猴子通过对与两个可能的运动方向对齐的两个目标之一进行扫视运动来报告感知到的运动方向。我们假设，这些神经元反映了通过对方向辨别任务的广泛训练形成的视觉运动方向和眼跳方向之间的学习关联。我们测试了这一假设，通过搜索方向选择性的视觉反应，在两只猴子已被训练来执行类似的运动辨别任务，其中刺激运动的方向是从操作性眼跳的方向分离。在这些猴子中没有强烈的方向性视觉反应，这与广泛的训练可以在SC神经元的亚群中诱导高度特异性视觉反应的概念一致。
In a previous report, we described a heretofore undetected population of neurons in the intermediate and deep layers of the monkey superior colliculus (SC) that yielded directionally selective visual responses to stimuli presented within the central 4° of the visual field. We observed these neurons in three monkeys that had been extensively trained to perform a visual direction discrimination task in this region of the visual field. The task required the monkeys to report the perceived direction of motion by making a saccadic eye movement to one of two targets aligned with the two possible directions of motion. We hypothesized that these neurons reflect a learned association between visual motion direction and saccade direction formed through extensive training on the direction discrimination task. We tested this hypothesis by searching for direction-selective visual responses in two monkeys that had been trained to perform a similar motion discrimination task in which the direction of stimulus motion was dissociated from the direction of the operant saccade. Strongly directional visual responses were absent in these monkeys, consistent with the notion that extensive training can induce highly specific visual responses in a subpopulation of SC neurons.