Acid-Base Jointly Promoted Copper(I)-Catalyzed Azide-Alkyne Cycloaddition
Acid-Base Jointly Promoted Copper(I)-Catalyzed Azide-Alkyne Cycloaddition
复制标题
酸碱联合促进铜(I)催化叠氮化物-炔环加成
DOI：
10.1021/jo200869a
复制
发表时间：
2011-08-19
影响因子：
3.6
通讯作者：
Hu, Yuefei
中科院分区：
文献类型：
--
作者：
Shao, Changwei;Wang, Xinyan;Hu, Yuefei
In this novel acid-base jointly promoted CuAAC, the combination of CuI/DIPEA/HOAc was developed as a highly efficient catalytic system. The functions of DIPEA and HOAc have been assigned, and HOAc was recognized to accelerate the conversions of the C-Cu bond-containing intermediates and buffer the basicity of DIPEA. As a result, all drawbacks occurring in the popular catalytic system CuI/NR3 were overcome easily.
