Risk assessment of Clostridium perfringens in Cornish pasties in the UK
Risk assessment of Clostridium perfringens in Cornish pasties in the UK
复制标题
英国康沃尔馅饼中产气荚膜梭菌的风险评估
DOI：
10.1016/j.foodcont.2019.106822
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发表时间：
2020
期刊：
影响因子：
6
通讯作者：
M. Zwietering
中科院分区：
文献类型：
--
作者：
E. Gkogka;M. W. Reij;L. Gorris;M. Zwietering
为了评估与英国康沃尔馅饼消费相关的产气荚膜梭菌毒素感染的风险，建立了一个随机风险评估模型。暴露在病原体下的模拟结果是不同成分(即牛肉和胡椒)的污染，在室温下应用不同的冷却方案，并考虑一些常见大小的糕点。该模型预测，英国每年平均每百万人有213例胃肠炎(95%可信区间：128-317)，根据流行病学数据，这可能解释了每年产气荚膜梭菌感染的很大比例。影响这一估计的主要因素和可能的干预目标是消费时间和受污染成分中病原体的浓度，在不同的干预方案中测试了这些因素在降低风险方面的影响。该模型的结果与一些可能的风险缓解措施一起作为基础，讨论了在食品安全决策的背景下将基于风险的衡量标准作为风险管理选择的可能性。
To assess the risk ofC.perfringenstoxico-infections related to the consumption of Cornish pasties in the United Kingdom, a stochastic risk assessment model was created. Exposure to the pathogen was modelled as the result of contamination of different ingredients (i.e. beef and pepper), application of different cooling scenarios at room temperature and considering pasties of a number of common sizes. The model predicted a mean of 213 cases of gastroenteritis per million people in the UK per year (95% CI: 128–317), which might explain a significant proportion of annualC.perfringenstoxico-infections according to epidemiological data. Major factors influencing this estimate and possible targets for interventions were the time to consumption and the concentration of the pathogen in contaminated ingredients, the impact of which in reducing the risk was tested in different intervention scenarios. The results of the model together with a number of possible risk mitigation measures are used as a basis to discuss the potential of setting of risk-based metrics as a risk management option in the context of food safety decision-making.