Phospholipid nonwoven electrospun membranes
Phospholipid nonwoven electrospun membranes
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DOI：
10.1126/science.1119790
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发表时间：
2006-01-20
期刊：
影响因子：
56.9
通讯作者：
Long, TE
中科院分区：
文献类型：
--
作者：
McKee, MG;Layman, JM;Long, TE
非织造纤维膜由静电纺丝卵磷脂溶液在单个加工步骤中形成。随着卵磷脂浓度的增加，胶束形态从球形演变为圆柱形，并且在较高浓度下，圆柱形胶束以类似于半稀释或浓缩溶液中的聚合物的方式重叠和缠结。在高于蠕虫状胶束缠结开始的浓度下，制造直径为1至5微米的电纺纤维。静电纺丝磷脂纤维提供了直接制造基于生物的高表面积膜的可能性，而无需使用多个合成步骤、复杂的静电纺丝设计或后处理表面处理。
Nonwoven fibrous membranes were formed from electrospinning lecithin solutions in a single processing step. As the concentration of lecithin increased, the micellar morphology evolved from spherical to cylindrical, and at higher concentrations the cylindrical micelles overlapped and entangled in a fashion similar to polymers in semi-dilute or concentrated solutions. At concentrations above the onset of entanglements of the wormlike micelles, electrospun fibers were fabricated with diameters on the order of 1 to 5 micrometers. The electrospun phospholipid fibers offer the potential for direct fabrication of biologically based, high-surface-area membranes without the use of multiple synthetic steps, complicated electrospinning designs, or postprocessing surface treatments.