Programming Molecular Association and Viscoelastic Behavior in Protein Networks
Programming Molecular Association and Viscoelastic Behavior in Protein Networks
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DOI：
10.1002/adma.201506216
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发表时间：
2016-06-15
影响因子：
29.4
通讯作者：
Tirrell, David A.
中科院分区：
文献类型：
--
作者：
Dooling, Lawrence J.;Buck, Maren E.;Tirrell, David A.
本发明描述了一组重组人工蛋白，其可以通过共价键或螺旋结构域的缔合或两者交联。所设计的蛋白质可用于构建分子网络，其中交联机制决定了对机械变形的时间依赖性响应。
A set of recombinant artificial proteins that can be crosslinked, by either covalent bonds or association of helical domains or both, is described. The designed proteins can be used to construct molecular networks in which the mechanism of crosslinking determines the time-dependent responses to mechanical deformation.