EBV-associated synovial lymphoma in a chronically inflamed joint in rheumatoid arthritis receiving prolonged methotrexate treatment.
EBV-associated synovial lymphoma in a chronically inflamed joint in rheumatoid arthritis receiving prolonged methotrexate treatment.
复制标题
接受长期甲氨蝶呤治疗的类风湿性关节炎慢性发炎关节中的 EBV 相关滑膜淋巴瘤。
作者：
C. Chim;Y. Y. Pang;G. Ooi;M. Mok;T. Shek
长期类风湿性关节炎（RA）的患者在接受长期甲氨蝶呤治疗时发生慢性炎症膝关节肿胀。磁共振成像和正电子发射断层扫描显示软组织肿胀与强烈的示踪剂摄取。活检证实是高级别B细胞淋巴瘤他在利妥昔单抗加CEOP治疗后完全缓解。本文对慢性炎症和甲氨蝶呤在RA淋巴瘤发病中的作用进行了讨论。
A patient with longstanding rheumatoid arthritis (RA) developed swelling in a chronically inflamed knee joint while receiving prolonged methotrexate treatment. Magnetic resonance imaging and positron-emission tomography showed soft tissue swelling with intense tracer uptake. Biopsy confirmed high-grade B-cell lymphoma. He developed complete remission with rituximab plus CEOP. The role of chronic inflammation and methotrexate in the pathogenesis of lymphoma in RA was discussed.
影响因子：
10.3
作者：
Feng, WH;Cohen, JI;Kenney, SC
通讯作者：
Kenney, SC