Laser Therapy in the Treatment of Diabetic Retinopathy and Diabetic Macular Edema.

Laser Therapy in the Treatment of Diabetic Retinopathy and Diabetic Macular Edema.
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DOI:
10.1007/s11892-021-01403-6
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发表时间:
2021-09-06
影响因子:
4.2
通讯作者:
Paulus YM
Paulus YM
中科院分区:
医学2区
文献类型:
--
作者:
Everett LA;Paulus YM

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本文综述了激光治疗糖尿病视网膜病变和糖尿病黄斑水肿的适应症和证据。特别重点放在传统激光光凝与更现代的激光光凝技术的优点和局限性上,以及激光光凝在糖尿病视网膜病变和糖尿病黄斑水肿治疗中的作用,经常使用药物治疗,包括抗血管内皮生长因子(VEGF)治疗。激光光凝仍然是有效、明确治疗PDR的金标准疗法,在治疗二甲醚方面也非常有效。然而,最近的许多研究已经证明了联合药物治疗的临床疗效和改善的功能和解剖结果。激光技术的不断创新和对激光-视网膜相互作用和病理生理学的不断了解表明,激光治疗将在未来许多年继续在糖尿病视网膜病变和糖尿病黄斑水肿的治疗中发挥关键作用。
This review highlights indications and evidence on laser therapy in the management of diabetic retinopathy and diabetic macular edema. Particular focus is placed upon the benefits and limitations of conventional laser photocoagulation versus more modern laser photocoagulation techniques, as well as the role of laser photocoagulation in treatment of diabetic retinopathy and diabetic macular edema with the frequent utilization of pharmacologic, including anti-vascular endothelial growth factor (VEGF), therapy. Laser photocoagulation remains the gold-standard therapy for the effective, definitive treatment of PDR, and also is highly effective in the management of DME. However, numerous recent studies have demonstrated the clinical efficacy and improved functional and anatomic outcomes of combination therapy with pharmacologic treatment. Continuing innovations in laser technology and improved understanding of laser-retinal interactions and pathophysiology demonstrate that laser therapy will continue to play a critical role in the treatment of diabetic retinopathy and diabetic macular edema for many years to come.
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